Evidence map›Paper›PMID 39976719›Full record

ReviewNaunyn-Schmiedeberg's archives of pharmacology2025

Marine life as a source of anti-prostate cancer agents: an updated overview (2003-2023).

Amjad Hussain, Ammara Sohail, Muhammad Sajid Hamid Akash, Sarosh Iqbal, Kanwal Rehman, Muhammad Imran, Shoaib Khan, Muhammad Adnan Ayub, Daijie Wang, Dildar Ahmed and 3 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Naunyn-Schmiedeberg's archives of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Amjad HussainInstitute of Chemistry, University of Okara, Okara, 56300, Pakistan. amjadhussain@uo.edu.pk.
Ammara SohailInstitute of Chemistry, University of Okara, Okara, 56300, Pakistan.
Muhammad Sajid Hamid AkashDepartment of Pharmaceutical Chemistry, Government College University, Faisalabad, Pakistan.
Sarosh IqbalDepartment of Applied Chemistry, Government College University, Faisalabad, Faisalabad, 38000, Pakistan.
Kanwal RehmanDepartment of Pharmacy, The Women University, Multan, Pakistan.
Muhammad ImranDepartment of Chemistry, Faculty of Science, Research Center for Advanced Materials Science (RCAMS), King Khalid University, P.O. Box 9004, 61413, Abha, Saudi Arabia.
Shoaib KhanDepartment of Chemistry, Abbottabad University of Science and Technology (AUST), Havelian, 22500, Abbottabad, Pakistan.
Muhammad Adnan AyubDepartment of Chemistry, University of Sahiwal, Sahiwal, 57000, Punjab, Pakistan.
Daijie WangSchool of Pharmaceutical Sciences and Key Laboratory for Applied Technology of Sophisticated Analytical Instruments of Shandong Province, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China.
Dildar AhmedDepartment of Chemistry, Forman Christian College University, Lahore, Pakistan.
Mohammed Hadi Ali Al-JumailiDepartment of Applied Chemistry, College of Applied Science, University of Fallujah, Al-Anbar, Iraq.
Maria BashirInstitute of Chemistry, University of Okara, Okara, 56300, Pakistan.
Mariam RasoolDepartment of Applied Chemistry, Government College University, Faisalabad, Faisalabad, 38000, Pakistan.

Funding

Muhammad Imran R.G.P. 2/232/45
6 · The paper itself

Abstract

Cancer is the deadliest threat that human beings are currently facing. Prostate cancer is the second largest cancer in males all over the world. During the last decade, scientists made breakthroughs in combatting this deadliest threat through naturally identified drugs. As in the majority of the cases, the natural products have been reported as non-toxic to the healthy cells of the body; therefore, scientists are taking special interest in identifying those and making tiresome efforts to isolate compounds from the naturally occurring living resources. Marine natural products are given a special preference over other natural products because of their diverse atmospheric and structural variations as well as signaling pathways for carcinogenesis. This study covers the anti-prostate cancer agents extracted from marine organisms including algae, fungi, bacteria, sponges, soft-bodied corals, fish, and other miscellaneous organisms. These natural products belong to different classes such as terpenes, terpenoids, carotenoids, alkaloids, polyketides, peptides, lactones, quinones, polysaccharides, and steroids. These compounds act against prostate cancer cells via in vitro and in vivo pathways, show special affinity towards the targeted area, and are specific because they bind to specific signaling paths. This review article covers data published from 2003 to 2023, which consists of anti-prostate cancer agents from marine sources.

Indexed as

Antineoplastic AgentsAquatic OrganismsBiological ProductsProstatic NeoplasmsAnimalsHumansMaleAntineoplastic AgentsBiological ProductsAnti-prostate cancer agentsCarcinogenesisMarine natural productsProstate cancer

Identifiers

PMID39976719

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.