Evidence map›Paper›PMID 39976435›Full record

ArticlemBio2025

Large-scale genomic analysis reveals significant role of insertion sequences in antimicrobial resistance of

Fei Xie, Lifeng Wang, Song Li, Long Hu, Yanhua Wen, Xuming Li, Kun Ye, Zhimei Duan, Qi Wang, Yuanlin Guan and 5 more

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  7. Review
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  10. Article
  11. Identification and genome insights intoFrontiers in plant science · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Fei Xie *College of Pulmonary and Critical Care Medicine, Chinese PLA General Hospital, Beijing, China.ORCID 0000-0003-3674-8216
Lifeng Wang *Laboratory Medicine Department, First Medical Center of Chinese PLA General Hospital, Beijing, China.
Song Li *Department of Research and Development, Hugobiotech Co., Ltd, Beijing, China.ORCID 0000-0002-8992-487X
Long Hu *Department of Research and Development, Hugobiotech Co., Ltd, Beijing, China.
Yanhua Wen *Department of Research and Development, Hugobiotech Co., Ltd, Beijing, China.ORCID 0009-0002-6867-4602
Xuming LiDepartment of Research and Development, Hugobiotech Co., Ltd, Beijing, China.ORCID 0000-0002-5049-9706
Kun YeLaboratory Medicine Department, First Medical Center of Chinese PLA General Hospital, Beijing, China.
Zhimei DuanCollege of Pulmonary and Critical Care Medicine, Chinese PLA General Hospital, Beijing, China.
Qi WangDepartment of Research and Development, Hugobiotech Co., Ltd, Beijing, China.
Yuanlin GuanDepartment of Research and Development, Hugobiotech Co., Ltd, Beijing, China.
Ye ZhangDepartment of Research and Development, Hugobiotech Co., Ltd, Beijing, China.
Qiqi ShiDepartment of Research and Development, Hugobiotech Co., Ltd, Beijing, China.
Jiyong YangLaboratory Medicine Department, First Medical Center of Chinese PLA General Hospital, Beijing, China.ORCID 0000-0002-1194-175X
Han XiaDepartment of Research and Development, Hugobiotech Co., Ltd, Beijing, China.ORCID 0000-0002-5179-0255
Lixin XieCollege of Pulmonary and Critical Care Medicine, Chinese PLA General Hospital, Beijing, China.ORCID 0000-0002-1091-2041

Funding

Capital's Funds for Health Improvement and Research 2022-1-5091MOST | National Natural Science Foundation of China (NSFC) 61976223Program 23SWAQ12Program BLB20J002
6 · The paper itself

Abstract

IMPORTANCE: The interplay between insertion sequences (ISs) and antibiotic resistance genes (ARGs) in

Indexed as

Acinetobacter baumanniiAnti-Bacterial AgentsDNA Transposable ElementsDrug Resistance, BacterialGenome, BacterialAcinetobacter InfectionsGenomicsHigh-Throughput Nucleotide SequencingHumansMachine LearningMicrobial Sensitivity TestsPhenotypeAnti-Bacterial AgentsDNA Transposable Elementsantimicrobial resistanceinsertion sequenceIS-ARG pairsrandom-forest

Identifiers

PMID39976435
PMCPMC11898611

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.