Evidence map›Paper›PMID 39976406›Full record

ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2025

Reading tree leaves: inferring speciation anfd extinction processes using phylogenies.

Bruce Rannala, Ziheng Yang

Abstract readReview
In one paragraph

Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. "A mathematical theory of evolution": phylogenetic models dating back 100 years.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Bruce RannalaDepartment of Evolution and Ecology, University of California, Davis, CA 95616, USA.ORCID 0000-0002-8355-9955
Ziheng YangDepartment of Genetics, Evolution, and Environment, University College London, London WC1E 6BT, UK.ORCID 0000-0003-3351-7981

Funding

Biotechnology and Biological Sciences Research CouncilJohn Templeton FoundationNIH
6 · The paper itself

Abstract

The birth-death process (BDP) is widely used in evolutionary biology as a model for generating phylogenetic trees of species. The generalized birth-death process (GBDP) allows rate variation over time, with speciation and extinction rates to be arbitrary functions of time. Here we review the probability theory underpinning the GBDP as a model of cladogenesis and recent findings concerning its identifiability. The GBDP with arbitrary continuous rate functions has been shown to be non-identifiable from lineage-through-time data: even with species phylogenies of infinite size the parameters cannot be estimated. However, a restricted class of BDPs with piecewise-constant rates has been shown to be identifiable. We review and illustrate these results using simple examples and discuss their implications for biologists interested in inferring the past tempo and mode of evolution using reconstructed phylogenetic trees.This article is part of the theme issue '"A mathematical theory of evolution": phylogenetic models dating back 100 years'.

Indexed as

Extinction, BiologicalGenetic SpeciationPhylogenyModels, Geneticgeneralized birth–death processidentifiabilityphylogenetic treesstatistical inferenceYule process

Identifiers

PMID39976406
PMCPMC11867106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.