Evidence map›Paper›PMID 39976034›Full record

ReviewCurrent stem cell research & therapy2025

Fasting the Stem Cells to Boost their Metabolic Functions.

Pedro Henrique Maglio França, Giovanna Rosa Degasperi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current stem cell research & therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Pedro Henrique Maglio FrançaCollege of Veterinary Medicine, Pontifical Catholic University of Campinas, SP, Brazil.
Giovanna Rosa DegasperiPostgraduate Program in Health Sciences, Pontifical Catholic University of Campinas, SP, Brazil.ORCID 0000-0002-0317-2532

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tissue homeostasis and regeneration depend on differentiated stem cells into specialized cell types. Dietary interventions, such as caloric restriction, are critical regulators of stem cell functions by altering their metabolism. This review discusses recent studies illustrating how diet interventions impact stem cell function. We summarize molecular targets and physiological effects of different types of caloric restriction and ketogenic mimicking diets in stem cells from bone marrow, muscle, and intestine. Furthermore, we highlight the nutrient-sensing pathway target of stem cells during caloric restriction. Understanding how nutrient signaling controls stem cell fate decisions is important to developing dietary interventions to improve the clinical application of stem cells.

Indexed as

FastingStem CellsAnimalsCaloric RestrictionCell DifferentiationDiet, KetogenicHumansSignal Transductioncaloric restrictionDietary interventionsfastingketogenic dietmetabolismmTORC.stem cells

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.