Evidence map›Paper›PMID 39975943›Full record

ReviewCurrent sleep medicine reports2025

Integrating Assessment of Circadian Rhythmicity to Improve Treatment Outcomes for Circadian Rhythm Sleep-Wake Disorders: Updates on New Treatments.

Gabrielle F Gloston, Katherine C Ward, G Carolina Rodriguez-Torres, Karen L Gamble, S Justin Thomas

Abstract readReview
In one paragraph

Review in Current sleep medicine reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gabrielle F GlostonDepartment of Psychology, University of Alabama at Birmingham, Birmingham, AL USA.
Katherine C WardDepartment of Psychology, University of Alabama at Birmingham, Birmingham, AL USA.
G Carolina Rodriguez-TorresDepartment of Psychiatry & Behavioral Neurobiology, Heersink School of Medicine, University of Alabama at Birmingham, 1720 2nd Ave S, Birmingham, AL 35294-0017 USA.
Karen L GambleDepartment of Psychiatry & Behavioral Neurobiology, Heersink School of Medicine, University of Alabama at Birmingham, 1720 2nd Ave S, Birmingham, AL 35294-0017 USA.
S Justin ThomasDepartment of Psychiatry & Behavioral Neurobiology, Heersink School of Medicine, University of Alabama at Birmingham, 1720 2nd Ave S, Birmingham, AL 35294-0017 USA.

Funding

Sleep and Circadian Contributions to Nighttime Blood Pressure Rhythms (SCN-BP)R01HL167230 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Stephen J Thomas · 2023 to 2026
$2.4M
NHLBI NIH HHS R01 HL167230
6 · The paper itself

Abstract

Purpose of Review: Despite advancements in basic circadian research, development of new diagnostic and treatment strategies for circadian rhythm sleep-wake disorders (CRSWDs) has been slow. Here, we review the most recent innovations in human circadian assessment and emerging new therapies for CRSWDs. Recent Findings: Researchers have improved existing circadian assessment methods to overcome logistical barriers and developed novel circadian assessment methods. New treatments for CRSWDs involve pharmacological and behavioral treatments that modulate circadian phase, amplitude, and/or robustness of the central circadian clock. Summary: Commercialization of these emerging tools will require overcoming barriers, such as additional testing to confirm the underlying pathology and mechanism of action of potential treatments. Clinicians and scientists are also called to survey adjacent fields and adopt existing diagnostic tools that may offer diagnostic clarity in CRSWDs. Lastly, we must continue to advocate for medical insurance coverage of current and future tools and technologies to improve patient care.

Indexed as

Circadian phaseCircadian rhythm assessmentCircadian rhythm sleep-wake disordersCircadian rhythm treatmentsEntrainment

Identifiers

PMID39975943
PMCPMC11832606

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.