Evidence map›Paper›PMID 39975885›Full record

ArticleResearch square2025

Performance of Molecular Inversion Probe DR23K and Paragon MAD4HatTeR Amplicon Sequencing Panels for Detection of Plasmodium falciparum Mutations Associated with Antimalarial Drug Resistance.

Thomas Katairo, Victor Asua, Bienvenu Nsengimaana, Stephen Tukwasibwe, Francis D Semakuba, Innocent Wiringilimaana, Shreeya Garg, Shahiid Kiyaga, Monica Mbabazi, Kisakye D Kabbale and 10 more

Abstract readPreprint
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

Thomas KatairoInfectious Diseases Research Collaboration.
Victor AsuaInfectious Diseases Research Collaboration.
Bienvenu NsengimaanaInfectious Diseases Research Collaboration.
Stephen TukwasibweInfectious Diseases Research Collaboration.
Francis D SemakubaInfectious Diseases Research Collaboration.
Innocent WiringilimaanaInfectious Diseases Research Collaboration.
Shreeya GargUniversity of California, San Francisco.
Shahiid KiyagaInfectious Diseases Research Collaboration.
Monica MbabaziInfectious Diseases Research Collaboration.
Kisakye D KabbaleInfectious Diseases Research Collaboration.
Alisen AyitewalaUganda National Health Laboratory Services (UNHLS)/Central Public Health Laboratories (CPHL).
Samuel L NsobyaInfectious Diseases Research Collaboration.
Moses R KamyaInfectious Diseases Research Collaboration.
Issac SsewanyanaInfectious Diseases Research Collaboration.
Jeffrey A BaileyBrown University.
Andrés Aranda-DíazUniversity of California, San Francisco.
Philip J RosenthalUniversity of California, San Francisco.
Bryan GreenhouseUniversity of California, San Francisco.
Jessica BriggsUniversity of California, San Francisco.
Melissa D ConradUniversity of California, San Francisco.

Funding

Transmission ProjectU19AI089674 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MATTHEW G DORSEY, MOSES Robert KAMYA · 2010 to 2026
$29.3M
Resistance of Malaria Parasites to Artemisinin-Based TherapiesR01AI075045 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ROSENTHAL, PHILIP JON · 2009 to 2024
$8.4M
Surveillance to track and characterize antimalarial resistance trends in Ugandan Plasmodium falciparum parasites (STARTUP)R01AI173557 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Melissa D Conrad · 2023 to 2026
$2.9M
Mentoring translational scientists in international infectious disease researchK24AI144048 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Bryan R Greenhouse · 2019 to 2026
$1.6M
Gates Foundation INV-035751Gates Foundation INV-037316NIAID NIH HHS K24 AI144048NIAID NIH HHS R01 AI075045NIAID NIH HHS R01 AI173557NIAID NIH HHS U19 AI089674
6 · The paper itself

Abstract

Background: Molecular surveillance of drug-resistant Methods: To compare the performance of DR23K and MAD Results: Across the four parasite densities, MAD Conclusions: MAD

Indexed as

Antimalarial drug resistanceDR23KMAD4HatTeRMicrohaplotypesMolecular Inversion ProbesPrecisionSensitivitySNPsUganda

Identifiers

PMID39975885
PMCPMC11838754

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.