Osteofibrous dysplasia of the 8th rib: a case report.

Osteofibrous dysplasia (OFD) is a rare benign bone lesion primarily affecting the long bones' anterior cortex, commonly observed in adolescents. Typically found in the tibia and fibula, it represents less than 1% of primary bone tumors. While OFD is predominantly seen in the lower extremities, occurrences in ribs, particularly in adult females, are exceptionally rare. Distinguishing OFD from fibrous dysplasia and OFD-like adamantinoma is crucial due to distinct clinical and histopathological features. We illustrate an interesting clinical course of a 28-year-old adult female with monostotic OFD involving the right 8th rib, who was clinically and radiologically suspected to be having fibrous dysplasia (FD). However, histopathological examination assisted in the confirmation of the final diagnosis of OFD. This report presents a case of OFD in the 8th rib of a 28-year-old female, highlighting the diagnostic challenge and emphasizing the importance of accurate diagnosis for appropriate management. The rarity of this presentation underscores the need for further research to elucidate the clinical spectrum and optimal management strategies for OFD in unusual anatomical locations.