Evidence map›Paper›PMID 39975376›Full record

ArticlebioRxiv : the preprint server for biology2025

Heterozygosity at a conserved candidate sex determination locus is associated with female development in the clonal raider ant (

Kip D Lacy, Jina Lee, Kathryn Rozen-Gagnon, Wei Wang, Thomas S Carroll, Daniel J C Kronauer

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Kip D LacyLaboratory of Social Evolution and Behavior, The Rockefeller University, New York, NY, USA.ORCID 0000-0002-3149-8927
Jina LeeLaboratory of Social Evolution and Behavior, The Rockefeller University, New York, NY, USA.
Kathryn Rozen-GagnonDepartment of Molecular Genetics, University of Toronto, Toronto, Canada.
Wei WangBioinformatics Resource Center, The Rockefeller University, New York, NY, USA.
Thomas S CarrollBioinformatics Resource Center, The Rockefeller University, New York, NY, USA.
Daniel J C KronauerLaboratory of Social Evolution and Behavior, The Rockefeller University, New York, NY, USA.ORCID 0000-0002-4103-7729

Funding

The Molecular Underpinnings of Complex Social BehaviorR35GM127007 · NIGMS · ROCKEFELLER UNIVERSITY · PI KRONAUER, DANIEL · 2018 to 2022
$2.6M
NIGMS NIH HHS R35 GM127007
6 · The paper itself

Abstract

Sex determination is a developmental switch that triggers sex-specific developmental programs. This switch is "flipped" by the expression of genes that promote male- or female-specific development. Many lineages have evolved sex chromosomes that act as primary signals for sex determination. However, haplodiploidy (males are haploid and females are diploid), which occurs in ca. 12% of animal species, is incompatible with sex chromosomes. Haplodiploid taxa must, therefore, rely on other strategies for sex determination. One mechanism, "complementary sex determination" (CSD), uses heterozygosity as a proxy for diploidy. In CSD, heterozygosity at a sex determination locus triggers female development, while hemizygosity or homozygosity permits male development. CSD loci have been mapped in honeybees and two ant species, but we know little about their evolutionary history. Here, we investigate sex determination in the clonal raider ant,

Identifiers

PMID39975376
PMCPMC11838215

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.