ArticlebioRxiv : the preprint server for biology2025
Bacterial IF2's N-terminal IDR drives cold-induced phase separation and promotes fitness during cold stress.
Aishwarya Ghosh, Kaveendya S Mallikaarachchi, Kathryn G Dzurik, Vidhyadhar Nandana, Nathaniel R Nunez, W Seth Childers, Jared M Schrader
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
7 authors.
Aishwarya GhoshDepartments of Chemistry and Biological Sciences, Wayne State University, Detroit, MI.
Kaveendya S MallikaarachchiDepartments of Chemistry and Biological Sciences, Wayne State University, Detroit, MI.
Kathryn G DzurikDepartment of Chemistry, University of Pittsburgh, Pittsburgh, PA.
Vidhyadhar NandanaDepartments of Chemistry and Biological Sciences, Wayne State University, Detroit, MI.
Nathaniel R NunezDepartments of Chemistry and Biological Sciences, Wayne State University, Detroit, MI.
Jared M SchraderDepartments of Chemistry and Biological Sciences, Wayne State University, Detroit, MI.ORCID 0000-0002-5728-5882 Funding
Research Enhancement for BUILDing Detroit (ReBUILDetroit)TL4GM118983 · NIGMS · UNIVERSITY OF DETROIT MERCY · PI BRYANT-FRIEDRICH, AMANDA C, SNYDER, KATHERINE E · 2015 to 2023
$17.0MResearch Enhancement for BUILDing Detroit (ReBUILDetroit)UL1GM118982 · NIGMS · UNIVERSITY OF DETROIT MERCY · PI SNYDER, KATHERINE E · 2015 to 2023
$10.8MResearch Enhancement for BUILDing Detroit (ReBUILDetroit)RL5GM118981 · NIGMS · UNIVERSITY OF DETROIT MERCY · PI BRYANT-FRIEDRICH, AMANDA C, SNYDER, KATHERINE E · 2015 to 2023
$4.8MMechanisms of Non-Shine-Dalgarno Translation InitiationR35GM124733 · NIGMS · WAYNE STATE UNIVERSITY · PI Jared Michael Schrader · 2017 to 2026
$3.6MBiomolecular condensates as organizers of mRNA decay in bacteriaR01GM136863 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI William Seth Childers · 2020 to 2026
$1.9MNIGMS NIH HHS R01 GM136863NIGMS NIH HHS R35 GM124733NIGMS NIH HHS RL5 GM118981NIGMS NIH HHS TL4 GM118983NIGMS NIH HHS UL1 GM118982
6 · The paper itselfAbstract
Translation initiation factor 2 (IF2) plays an essential role in bacterial cells by delivering the fMet-tRNA
Indexed as
biomolecular condensatecold shockphase separationTranslation initiation factors
Identifiers
PMID39975289
PMCPMC11838494
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