Evidence map›Paper›PMID 39975253›Full record

ArticlebioRxiv : the preprint server for biology2025

Interferometric Ultra-High Resolution 3D Imaging through Brain Sections.

Hao-Cheng Gao, Fan Xu, Xi Cheng, Cheng Bi, Yue Zheng, Yilun Li, Tailong Chen, Yumian Li, Alexander A Chubykin, Fang Huang

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Hao-Cheng GaoWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA.
Fan XuWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA.
Xi ChengDepartment of Biological Science, Purdue University, West Lafayette, IN, USA.
Cheng BiWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA.
Yue ZhengWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA.
Yilun LiWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA.
Tailong ChenSchool of Optics and Photonics, Beijing Institute of Technology, Beijing 100081, China.
Yumian LiSchool of Optics and Photonics, Beijing Institute of Technology, Beijing 100081, China.
Alexander A ChubykinDepartment of Biological Science, Purdue University, West Lafayette, IN, USA.
Fang HuangWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA.

Funding

Ultra-high resolution structural and molecular imaging of cells and tissuesR35GM119785 · NIGMS · PURDUE UNIVERSITY · PI Fang Huang · 2016 to 2026
$4.8M
Ultra-high resolution, multiplexed single molecule nanoscopy and functional characterization of neural circuitsRF1MH123401 · NIMH · PURDUE UNIVERSITY · PI CHUBYKIN, ALEXANDER, HUANG, FANG · 2020 to 2020
$2.4M
NIGMS NIH HHS R35 GM119785NIMH NIH HHS RF1 MH123401
6 · The paper itself

Abstract

Single-molecule super-resolution microscopy allows pin-pointing individual molecular positions in cells with nanometer precision. However, achieving molecular resolution through tissues is often difficult because of optical scattering and aberrations. We introduced 4Pi single-molecule nanoscopy for brain with

Identifiers

PMID39975253
PMCPMC11838448

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.