Evidence map›Paper›PMID 39975243›Full record

ArticlebioRxiv : the preprint server for biology2025

EndoMAP.v1, a Structural Protein Complex Landscape of Human Endosomes.

Miguel A Gonzalez-Lozano, Ernst W Schmid, Enya Miguel Whelan, Yizhi Jiang, Joao A Paulo, Johannes C Walter, J Wade Harper

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Miguel A Gonzalez-LozanoDepartment of Cell Biology, Harvard Medical School, Boston MA, USA.ORCID 0000-0002-7837-151X
Ernst W SchmidDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston MA, USA.ORCID 0000-0002-4662-5298
Enya Miguel WhelanDepartment of Cell Biology, Harvard Medical School, Boston MA, USA.ORCID 0000-0003-1525-7207
Yizhi JiangDepartment of Cell Biology, Harvard Medical School, Boston MA, USA.ORCID 0000-0001-9016-1104
Joao A PauloDepartment of Cell Biology, Harvard Medical School, Boston MA, USA.ORCID 0000-0002-4291-413X
Johannes C WalterDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston MA, USA.ORCID 0000-0002-4186-7570
J Wade HarperDepartment of Cell Biology, Harvard Medical School, Boston MA, USA.ORCID 0000-0002-6944-7236

Funding

Endolysosomal Proteome Landscapes Through the Lens of Neurodegenerative Risk AllelesR01NS110395 · NINDS · HARVARD MEDICAL SCHOOL · PI JEFFREY W HARPER · 2018 to 2026
$4.1M
Advancing Multiplexed Isobaric Tag-based Strategies for Proteome ProfilingR01GM132129 · NIGMS · HARVARD MEDICAL SCHOOL · PI PAULO, JOAO A · 2019 to 2023
$1.7M
NIGMS NIH HHS R01 GM132129NINDS NIH HHS R01 NS110395
6 · The paper itself

Abstract

Early/sorting endosomes are dynamic organelles that play key roles in proteome control by triaging plasma membrane proteins for either recycling or degradation in the lysosome

Identifiers

PMID39975243
PMCPMC11839024

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.