Evidence map›Paper›PMID 39975206›Full record

ArticlebioRxiv : the preprint server for biology2025

Dynamics of infection and immunity over 50 years as marine stickleback adapt to freshwater.

Pranav Sriramulu, Dolph Schluter, Daniel I Bolnick

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Pranav SriramuluDepartment of Ecology and Evolutionary Biology, University of Connecticut, Storrs CT 06269 USA.
Dolph SchluterDepartment of Zoology, University of British Columbia, BC, Canada.
Daniel I BolnickDepartment of Ecology and Evolutionary Biology, University of Connecticut, Storrs CT 06269 USA.ORCID 0000-0003-3148-6296

Funding

Reciprocal genetics of recently-evolved vertebrate immunity and peritoneal helminth counter-adaptationR01AI123659 · NIAID · UNIVERSITY OF TEXAS AT AUSTIN · PI Daniel Imara Bolnick · 2017 to 2026
$3.8M
NIAID NIH HHS R01 AI123659
6 · The paper itself

Abstract

When a species colonizes a new environment, it may encounter new parasites to which its immune system is poorly adapted. After an initial spike in infection rates in the naïve founder population, the host may subsequently evolve increased immunity thereby reducing infection rates. Here, we present an example of this eco-evolutionary process, in a population of threespine stickleback (

Indexed as

biological invasionCestodeevolutionary immunologyfibrosishost-parasite interactionstickleback

Identifiers

PMID39975206
PMCPMC11838567

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.