Evidence map›Paper›PMID 39975155›Full record

ArticlebioRxiv : the preprint server for biology2025

Pleomorphic effects of three small-molecule inhibitors on transcription elongation by

Omar Herrera-Asmat, Alexander B Tong, Wenxia Lin, Tiantian Kong, Juan R Del Valle, Daniel G Guerra, Yon W Ebright, Richard H Ebright, Carlos Bustamante

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Omar Herrera-AsmatJason L. Choy Laboratory of Single-Molecule Biophysics, University of California, Berkeley, CA 94720.
Alexander B TongJason L. Choy Laboratory of Single-Molecule Biophysics, University of California, Berkeley, CA 94720.ORCID 0000-0003-3793-2533
Wenxia LinCalifornia Institute for Quantitative Biosciences, QB3, University of California, Berkeley, CA 94720.
Tiantian KongDepartment of Biomedical Engineering, School of Medicine, Shenzhen University, Shenzhen, Guangdong 518000, China.
Juan R Del ValleDepartment of Chemistry & Biochemistry, University of Notre Dame, IN 46556, USA.ORCID 0000-0002-8315-5264
Daniel G GuerraLaboratorio de Moléculas Individuales, Laboratorios de Investigación y Desarrollo, Facultad de Ciencias e Ingeniería, Universidad Peruana Cayetano Heredia, Av Honorio Delgado 430, San Martin de Porras, Lima 15102, Peru.ORCID 0000-0002-2410-722X
Yon W EbrightWaksman Institute, Rutgers University, Piscataway, NJ 08854.
Richard H EbrightWaksman Institute, Rutgers University, Piscataway, NJ 08854.
Carlos BustamanteJason L. Choy Laboratory of Single-Molecule Biophysics, University of California, Berkeley, CA 94720.ORCID 0000-0002-2970-0073

Funding

TRANSCRIPTION ACTIVATION BY CAPR01GM041376 · NIGMS · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI RICHARD H. EBRIGHT · 1989 to 2026
$6.5M
THE PHYSICAL CHEMISTRY OF NUCLEIC ACIDSR01GM032543 · NIGMS · UNIVERSITY OF OREGON · PI CARLOS Jose BUSTAMANTE · 1985 to 2026
$6.4M
BACTERIAL TRANSCRIPTION COMPLEXESR37GM041376 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI EBRIGHT, RICHARD H. · 2013 to 2022
$5.0M
NIGMS NIH HHS R01 GM032543NIGMS NIH HHS R01 GM041376NIGMS NIH HHS R37 GM041376
6 · The paper itself

Abstract

The

Identifiers

PMID39975155
PMCPMC11839117

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.