Evidence map›Paper›PMID 39974984›Full record

ArticlebioRxiv : the preprint server for biology2025

Dopamine signaling drives skin invasion by human-infective nematodes.

Ruhi Patel, Aracely Garcia Romero, Astra S Bryant, George W Agak, Elissa A Hallem

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Ruhi PatelDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0002-8612-0016
Aracely Garcia RomeroDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0002-7845-1296
Astra S BryantDepartment of Neurobiology and Biophysics, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0002-0887-2044
George W AgakDivision of Dermatology, Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0002-3356-9864
Elissa A HallemDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0003-0260-3174

Funding

MARC U*STAR Program at the University of California, Los AngelesT34GM008563 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MCEVOY, MEGAN M, POE, GINA R · 1996 to 2023
$9.7M
The Role of T cell Extracellular Traps in Acne PathogenesisR01AR081337 · NIAMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI George W Agak · 2022 to 2026
$2.2M
Mechanisms of skin penetration in skin-penetrating parasitic nematodesR01AI175183 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ELISSA ANYON HALLEM · 2024 to 2026
$1.9M
Dissecting the thermosensory biology of soil-transmitted parasitic nematodesDP2AI184544 · NIAID · UNIVERSITY OF WASHINGTON · PI Astra Shamgar Bryant · 2024 to 2026
$1.4M
The nature of Propionibacterium acnes-induced inflammatory immune responses in acne vulgarisK01AR071479 · NIAMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AGAK, GEORGE W · 2017 to 2022
$958k
Mechanosensory Behaviors of Skin-Penetrating Parasitic NematodesF32AI174816 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI PATEL, RUHI · 2023 to 2025
$226k
NIAID NIH HHS DP2 AI184544NIAID NIH HHS F32 AI174816NIAID NIH HHS R01 AI175183NIAMS NIH HHS K01 AR071479NIAMS NIH HHS R01 AR081337NIGMS NIH HHS T34 GM008563
6 · The paper itself

Abstract

Skin-penetrating nematodes are one of the most prevalent causes of disease worldwide - nearly 15% of the global population is infected with at least one species of skin-penetrating nematode

Identifiers

PMID39974984
PMCPMC11838280

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.