ArticlebioRxiv : the preprint server for biology2025
Lactate dehydrogenase is the Achilles' heel of Lyme disease bacterium
Ching Wooen Sze, Michael J Lynch, Kai Zhang, David B Neau, Steven E Ealick, Brian R Crane, Chunhao Li
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
7 authors.
Ching Wooen SzeDepartment of Oral Craniofacial Molecular Biology, Virginia Commonwealth University, Richmond, Virginia, 23298.
Michael J LynchDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, New York, 14853.ORCID 0000-0002-3569-4749 Kai ZhangDepartment of Oral Craniofacial Molecular Biology, Virginia Commonwealth University, Richmond, Virginia, 23298.
David B NeauDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, New York, 14853.
Steven E EalickDepartment of Microbiology and Immunology, Virginia Commonwealth University, Richmond, Virginia, 23298.
Brian R CraneDepartment of Microbiology and Immunology, Virginia Commonwealth University, Richmond, Virginia, 23298.ORCID 0000-0001-8234-9991 Chunhao LiDepartment of Oral Craniofacial Molecular Biology, Virginia Commonwealth University, Richmond, Virginia, 23298.
Funding
Training and OutreachP30GM124166 · NIGMS · CORNELL UNIVERSITY · PI RICHARD A. CERIONE · 2019 to 2026
$28.3MUnderstanding Unique Aspects of Motility and Chemotaxis in Borrelia burgdorferiR01AI078958 · NIAID · VIRGINIA COMMONWEALTH UNIVERSITY · PI Chunhao Chris Li · 2008 to 2026
$5.7MToward novel therapies against Lyme disease through the inhibition of lysinoalaine cross-linking in the bacterial flagella.R01AI148844 · NIAID · CORNELL UNIVERSITY · PI CRANE, BRIAN R, LI, CHUNHAO CHRIS · 2021 to 2024
$2.4MNIAID NIH HHS R01 AI078958NIAID NIH HHS R01 AI148844NIGMS NIH HHS P30 GM124166
6 · The paper itselfAbstract
As a zoonotic pathogen, the Lyme disease bacterium
Identifiers
PMID39974897
PMCPMC11839043
What OpenQuestion holds
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LicenceCC0
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