Evidence map›Paper›PMID 39974789›Full record

ArticleJournal of animal science and technology2025

Drone pupae extract enhances Hanwoo myosatellite cell function for cultivated meat production.

Nayoung Choi, Sanghun Park, Gyutae Park, Sehyuk Oh, Sol-Hee Lee, Junsoo Lee, Hyoyoung Kim, Geul Bang, Jungseok Choi

Abstract read
In one paragraph

Article in Journal of animal science and technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nayoung ChoiDepartment of Animal Science, Chungbuk National University, Cheongju 28644, Korea.ORCID https://orcid.org/0000-0002-4782-1098
Sanghun ParkDepartment of Animal Science, Chungbuk National University, Cheongju 28644, Korea.ORCID https://orcid.org/0000-0003-4804-0848
Gyutae ParkDepartment of Animal Science, Chungbuk National University, Cheongju 28644, Korea.ORCID https://orcid.org/0000-0003-1614-1097
Sehyuk OhDepartment of Animal Science, Chungbuk National University, Cheongju 28644, Korea.ORCID https://orcid.org/0000-0003-4105-2512
Sol-Hee LeeDepartment of Animal Science, Chungbuk National University, Cheongju 28644, Korea.ORCID https://orcid.org/0000-0003-1124-7095
Junsoo LeeDepartment of Food Science and Biotechnology, Chungbuk National University, Cheongju 28644, Korea.ORCID https://orcid.org/0000-0001-5557-4229
Hyoyoung KimDepartment of Agricultural Biology, National Institute of Agricultural Science, Rural Development Administration, Wanju 55365, Korea.ORCID https://orcid.org/0000-0002-9223-882X
Geul BangResearch Center for Bioconvergence Analysis, Korea Basic Science Institute, Cheongju 28119, Korea.ORCID https://orcid.org/0000-0002-8762-9877
Jungseok ChoiDepartment of Animal Science, Chungbuk National University, Cheongju 28644, Korea.ORCID https://orcid.org/0000-0001-8033-0410

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we analyzed effects of drone pupae aqueous extract powder (DEP) on proliferation and differentiation of Hanwoo myosatellite cells (HSC). Results of amino acid, vitamin, and mineral analysis of drone pupae revealed the presence of branched-chain amino acids, Glu, essential amino acids, vitamins B6, C and Mg, K, and so on. Additionally, drone pupae were shown to have an antioxidant ability. HSC were cultured for proliferation by adding 0, 10, 100, 200, and 400 μg/mL DEP to the medium. As a result of MTS analysis, DEP increased the proliferation capacity of HSC, with cell viability being significantly higher after treatment with DEP, especially when DEP was used at 100 μg/mL (p < 0.05). To measure the differentiation ability of HSC, 0 and 100 μg/mL DEP (CON, D100) were added to the medium, and cells were cultured. Myotube formation was confirmed through images using immunofluorescence staining. Fusion index and myotube area in the D100 were higher than those in the CON (

Indexed as

Cultivated meatDifferentiationDrone pupae extractFunctional substanceHanwoo myosatellite cellProliferation

Identifiers

PMID39974789
PMCPMC11833203

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.