Evidence map›Paper›PMID 39974716›Full record

ArticleFood chemistry: X2024

High-concentrate diet decreases lamb fatty acid contents by regulating bile acid composition.

Kaizhi Zheng, Liangyong Guo, Yang Cao, Yuyang Yin, Hui Gao, Xiaowei Zhang, Junfang Jiang, Jinbing Li, Xin Huang, Kui Li and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Food chemistry: X, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kaizhi ZhengInstitute of Animal Husbandry and Veterinary, Zhejiang, Academy of Agricultural Sciences, Hangzhou 310021, China.
Liangyong GuoHuzhou Academy of Agricultural Sciences, Huzhou 313000, China.
Yang CaoInstitute of Animal Husbandry and Veterinary, Zhejiang, Academy of Agricultural Sciences, Hangzhou 310021, China.
Yuyang YinHuzhou Academy of Agricultural Sciences, Huzhou 313000, China.
Hui GaoAnimal Husbandry Technology Promotion and Breeding Livestock and Poultry Monitoring Station of Zhejiang Province, Hangzhou 310000, China.
Xiaowei ZhangAnimal Husbandry Technology Promotion and Breeding Livestock and Poultry Monitoring Station of Zhejiang Province, Hangzhou 310000, China.
Junfang JiangInstitute of Animal Husbandry and Veterinary, Zhejiang, Academy of Agricultural Sciences, Hangzhou 310021, China.
Jinbing LiShangyu District Animal Husbandry and Veterinary Technology Promotion Center, Shaoxing 312300, China.
Xin HuangInstitute of Animal Husbandry and Veterinary, Zhejiang, Academy of Agricultural Sciences, Hangzhou 310021, China.
Kui LiAnimal Husbandry Technology Promotion and Breeding Livestock and Poultry Monitoring Station of Zhejiang Province, Hangzhou 310000, China.
Sangang HeInstitute of Animal Husbandry and Veterinary, Zhejiang, Academy of Agricultural Sciences, Hangzhou 310021, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Feeding sheep with high-concentrate diet (HCD) to shorten production cycle is a well-developed feeding strategy to increase lamb production. Here, metabolomics were performed to explore the mechanism that HCD changes lamb nutrition composition. Differential metabolites were enriched in primary bile acid biosynthesis. Significantly higher content of bile acids including taurodeoxycholic acid sodium salt (TDCA), taurochenodeoxycholic acid sodium salt (TCDCA) and taurocholic acid (TCA) was observed in lamb of HCD, while the content of lithocholic acid (LCA), cholic acid (CA), chenodeoxycholic acid (CDCA) and Chenodeoxycholic acid-3-beta-D-glucuronide (CDCA-3Gln) were higher in the controls. Furthermore, a significantly decreased content of fatty acids was observed in lamb of HCD group. Finally, primary skeletal cells treated with CA or TCA showed a significant decrease in contents of fatty acids, while TCA showed a stronger effect in decreasing fatty acid contents. Collectively, we suggest that HCD decreases lamb fatty acid contents by regulating bile acid composition.

Indexed as

Bile acidFatty acidHigh-concentrate dietLambMetabolomics

Identifiers

PMID39974716
PMCPMC11838137

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.