Comparative evaluation of three accidentally extruded sealers in periapical healing - An evidence - based study.

Background: The present study aimed to evaluate the periapical healing of root canal treatment after accidental extrusion and rate of resorption of three different base endodontic sealers. Materials and Methods: Seventy-five patients with single visit root canal treated teeth with accidental extrusion of sealer were selected based on inclusion and exclusion criteria and were allocated into three equal groups based on different base endodontic sealers used during obturation; Grossman, Sealapex™, and Seal-pex. Radiographic evaluation was done to assess periapical healing and rate of resorption at baseline, 1, 3, and 6 months. Statistical analysis was done using one-way repeated measured analysis of variance. Results: At the end of 6 months in Group 1 (Grossman), healing was rated as unchanged in 0 patients (0%), reduced in 0 patients (0%), almost absent in 2 patients (8%) and absent in 23 patients (92%). In Group 2 (sealapex), healing was rated as unchanged in 1 patient (4%), reduced in 6 patients (24%), almost absent in 6 patients (24%), and absent in 12 patients (48%). In Group 3 (seal-pex), healing was rated as unchanged in 2 patients (8%), reduced in 10 patients (40%), almost absent in 6 patients (24%) and absent in 7 patients (28%). Conclusions: Sealapex™ has shown better periapical lesion healing compared to Grossman Sealer and Seal-pex and Grossman Sealer had shown faster rate of resorption compared to Sealapex™ and seal-pex™.