ArticleJournal of conservative dentistry and endodontics2025
Effectiveness of silver-graphene oxide nanoparticle against Enterococcus faecalis biofilms in the root canal.
Article in Journal of conservative dentistry and endodontics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Time-dependent effect of nanoparticle-based intracanal medicament on root dentin microhardness and their antibacterial efficacy againstJournal of conservative dentistry and endodontics · 2026Article
- The conundrum of current endodontic disinfection strategies in microbial load reduction: a scoping review.BMC oral health · 2026Article
- Antibacterial efficacy of herbal extracts as photosensitizers in photodynamic root canal disinfection.Journal of conservative dentistry and endodontics · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aim: This study aims to assess the effectiveness of silver-graphene oxide (AgGO) nanoparticles against Enterococcus faecalis biofilm and smear layer in comparison with 3% sodium hypochlorite (NaOCl) and 2% chlorhexidine (CHX) using passive ultrasonic irrigation (PUI) technique. Subjects and Methods: Eighty single-rooted teeth were collected, sterilized, and prepared for this study. E. faecalis was inoculated into the root canals and incubated for 21 days. Teeth were divided into four groups for irrigation: Group I (0.25% AgGO), Group II (3% NaOCl), Group III (2% CHX), and Group IV (0.9% saline), followed by PUI. Microbiological evaluation was performed by collecting bacterial samples and quantifying colony-forming units/ml. Scanning electron microscope was used to assess biofilm and smear layer removal. Statistical Analysis Used: Kruskal-Wallis test, Bonferroni correction, intraclass correlation test. Results: Antibacterial activity and smear layer removal were highest in Group II followed by Group I and Group III which showed similar results. Group IV showed the least results. Conclusions: 3% NaOCl was the most effective solution in terms of antibacterial activity and smear layer removal. 0.25% AgGO and 2% CHX showed moderate effectiveness in removing E. faecalis biofilms and smear layer which suggests that both have potential as alternative irrigants.
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Registered trials
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