Evidence map›Paper›PMID 39974650›Full record

ArticleACS pharmacology & translational science2025

Synaptic Vesicle 2A (SV2A) Positron Emission Tomography (PET) Imaging as a Marker of Therapeutic Response in a Mouse Model of Depression.

Cassandre Corvo, Indira Mendez-David, Sébastien Goutal, Wadad Saba, Michel Bottlaender, Fabien Caillé, Rene Hen, Romain Colle, Emmanuelle Corruble, Nicolas Tournier and 2 more

Abstract read
In one paragraph

Article in ACS pharmacology & translational science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Synaptic density in the hippocampus of depressed patients: A quantitative electron microscopic study.Progress in neuro-psychopharmacology & biological psychiatry · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Cassandre CorvoUniversité Paris-Saclay, Inserm, CNRS, CEA, Laboratoire d'Imagerie Biomédicale Multimodale (BioMaps), Service Hospitalier Frédéric Joliot, 4 place du général Leclerc, Orsay 91401, France.
Indira Mendez-DavidUniversité Paris-Saclay, Centre de recherche en Epidémiologie et Santé des Populations (CESP-Inserm), UMR 1018, Team Moods, Orsay 91400, France.
Sébastien GoutalUniversité Paris-Saclay, Inserm, CNRS, CEA, Laboratoire d'Imagerie Biomédicale Multimodale (BioMaps), Service Hospitalier Frédéric Joliot, 4 place du général Leclerc, Orsay 91401, France.
Wadad SabaUniversité Paris-Saclay, Inserm, CNRS, CEA, Laboratoire d'Imagerie Biomédicale Multimodale (BioMaps), Service Hospitalier Frédéric Joliot, 4 place du général Leclerc, Orsay 91401, France.
Michel BottlaenderUniversité Paris-Saclay, Inserm, CNRS, CEA, Laboratoire d'Imagerie Biomédicale Multimodale (BioMaps), Service Hospitalier Frédéric Joliot, 4 place du général Leclerc, Orsay 91401, France.
Fabien CailléUniversité Paris-Saclay, Inserm, CNRS, CEA, Laboratoire d'Imagerie Biomédicale Multimodale (BioMaps), Service Hospitalier Frédéric Joliot, 4 place du général Leclerc, Orsay 91401, France.ORCID https://orcid.org/0000-0003-0088-7337
Rene HenDepartment of Psychiatry, Columbia University, New York, New York 10027, United States.
Romain ColleUniversité Paris-Saclay, Centre de recherche en Epidémiologie et Santé des Populations (CESP-Inserm), UMR 1018, Team Moods, Orsay 91400, France.
Emmanuelle CorrubleUniversité Paris-Saclay, Centre de recherche en Epidémiologie et Santé des Populations (CESP-Inserm), UMR 1018, Team Moods, Orsay 91400, France.
Nicolas TournierUniversité Paris-Saclay, Inserm, CNRS, CEA, Laboratoire d'Imagerie Biomédicale Multimodale (BioMaps), Service Hospitalier Frédéric Joliot, 4 place du général Leclerc, Orsay 91401, France.ORCID https://orcid.org/0000-0002-0755-2030
Claire LeroyUniversité Paris-Saclay, Inserm, CNRS, CEA, Laboratoire d'Imagerie Biomédicale Multimodale (BioMaps), Service Hospitalier Frédéric Joliot, 4 place du général Leclerc, Orsay 91401, France.ORCID https://orcid.org/0000-0002-7890-5980
Denis J DavidUniversité Paris-Saclay, Centre de recherche en Epidémiologie et Santé des Populations (CESP-Inserm), UMR 1018, Team Moods, Orsay 91400, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this preclinical pilot study, we used [

Identifiers

PMID39974650
PMCPMC11833719

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.