Evidence map›Paper›PMID 39974598›Full record

ArticleFrontiers in cardiovascular medicine2025

Risk factors for fluorouracil-induced cardiotoxicity in patients with gastrointestinal tumor.

Yuting Wu, Chen Lv, Jindong Li, Ying Ma, Xiaoli Zhu

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Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Yuting WuDepartment of Pharmacy, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, Jiangsu, China.
Chen LvDepartment of Medical Oncology, The People's Hospital of Hengshui, Hengshui, Hebei, China.
Jindong LiDepartment of Pharmacy, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, Jiangsu, China.
Ying MaDepartment of Pharmacy, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, Jiangsu, China.
Xiaoli ZhuDepartment of Pharmacy, The People's Hospital of Hengshui, Hengshui, Hebei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the risk factors for cardiotoxicity in patients with gastrointestinal (GI) tumors treated with fluorouracil drugs. Methods: This study included patients with GI tumors who received fluorouracil at our hospital between January 2018 and April 2022. The demographic and clinical characteristics were collected. The risk factors associated with the cardiotoxicity of fluorouracil were explored using multivariable logistic regression. Results: A total of 300 patients were finally included and divided into the cardiotoxicity ( Conclusion: Hyperlipidemia, diabetes, older age, treatment with capecitabine, and adjuvant radiotherapy might be independent risk factors for the cardiotoxicity of fluorouracil in patients with GI tumors.

Indexed as

cardiotoxicitychemotherapyfluorouracil drugsgastrointestinal neoplasmsrisk factors

Identifiers

PMID39974598
PMCPMC11835890

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.