Spectrum of Upper Gastrointestinal Diseases in Patients Presenting with Dyspepsia-A First Report from Myanmar.

Background: Dyspepsia is associated with a variety of benign and malignant gastrointestinal diseases. The aim of the study was to evaluate the spectrum of upper gastrointestinal endoscopic findings in patients presenting with dyspepsia. Methods: This is a retrospective study on consecutive patients with dyspepsia undergoing upper gastrointestinal endoscopy at the gastroenterology department of Thingangyun General Hospital, University of Medicine 2, Yangon, from January 1, 2017, to December 31, 2019. Results: In this study, 1650 patients were recruited retrospectively. Forty-nine patients were excluded due to incomplete data entry. There were 883 female (55%) out of 1601 patients. The mean age was 50.5 ± 15.82 years. The endoscopic findings were gastric/duodenal erosion (10.8%), erosive esophagitis (5.1%), duodenal ulcer (3.5%), gastric ulcer (4.4%), gastroesophageal varices (3.49%), esophageal cancer (0.8%), and gastric cancer (5.3%); in which early-onset gastric cancer contributed for 17.6%. Miscellaneous diagnoses were 4.2%, and findings were normal at 62.5%. Significant endoscopy findings were diagnosed in patients over 45 years of age. Conclusion: Significant endoscopic findings in dyspeptic patients are frequent in our data. A considerable number of gastric cancer were diagnosed in patients under 45 years of age.