ArticleAesthetic surgery journal. Open forum2025
Botulinum Toxin in Aesthetic Medicine: A Bibliometric Analysis of Research Trends and Methodological Quality of the Top 100 Cited Publications.
Article in Aesthetic surgery journal. Open forum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Botulinum toxin is widely used in aesthetic medicine, with numerous studies examining its efficacy and safety. Objectives: This bibliometric analysis aims to describe research trends and assess the methodological quality of the highest-impact botulinum toxin research in aesthetic applications. Methods: The authors of this study identified the 100 most-cited publications on botulinum toxin in aesthetics using Web of Science, covering all available journal years (from inception to October 2024). The Oxford Centre for Evidence-Based Medicine Level of Evidence (LOE) was used to assess the methodological quality of each study. Results: The authors identified 1728 articles on the aesthetic uses of botulinum toxin, with the top 100 most-cited articles spanning from 1994 to 2021. The United States dominated the research landscape with 50 articles, followed by Canada (15). The University of California (United States) and the University of British Columbia (Canada) emerged as the top contributing institutions. Among journals, Conclusions: This bibliometric analysis reveals a paucity of high-quality studies in the field of botulinum toxin in aesthetic medicine, with research predominantly concentrated in western countries. These findings highlight the need for more rigorous, evidence-based studies and increased global collaboration to advance the understanding and application of botulinum toxin in aesthetics. Level of Evidence 4 Therapeutic:
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.