Evidence map›Paper›PMID 39974436›Full record

ArticleMaedica2024

Fibromas and Infertility. What is the Role of Myomectomy in the Improvement of Fertility?

Konstantinos Nikolettos, Sonia Kotanidou, Panagiotis Tsikouras, Christos Damaskos, Nikolaos Garmpis, Emmanouil Kontomanolis, Aggeliki Gerede, Nikos Nikolettos, Aggelos Daniilidis

Abstract readEditorial
In one paragraph

Article in Maedica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Surgical management of uterine fibroids.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Review
  2. An exploratory study on the impact of endocrine and infectious comorbidities on reproductive outcomes after Palmer-type neosalpingostomy.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Konstantinos NikolettosObstetric and Gynecologic Clinic, Medical School, Democritus University of Thrace,Alexandroupolis, Greece.
Sonia KotanidouObstetric and Gynecologic Clinic, Medical School, Democritus University of Thrace,Alexandroupolis, Greece.
Panagiotis TsikourasObstetric and Gynecologic Clinic, Medical School, Democritus University of Thrace,Alexandroupolis, Greece.
Christos DamaskosRenal Transplantation Unit, Laiko General Hospital, Athens, Greece.
Nikolaos GarmpisSurgical Department, Sotiria General Hospital, Athens, Greece.
Emmanouil KontomanolisObstetric and Gynecologic Clinic, Medical School, Democritus University of Thrace,Alexandroupolis, Greece.
Aggeliki GeredeObstetric and Gynecologic Clinic, Medical School, Democritus University of Thrace,Alexandroupolis, Greece.
Nikos NikolettosObstetric and Gynecologic Clinic, Medical School, Democritus University of Thrace,Alexandroupolis, Greece.
Aggelos Daniilidis1st Department in Obstetrics and Gynecology, Papageorgiou General Hospital,School of Medicine, Aristotle University of Thessaloniki, 54643, Thessaloniki, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionUterine fibroids, also known as myomas, are benign tumors that develop from the smooth muscle cells of the uterus. Fibroids are estimated to occur predominantly in 20% to 40% of women of reproductive age, in whom they can cause symptoms like pressure, discomfort and excessive hemorrhage. EVIDENCE ACQUISITION: Precise assessment of fibroid size, number and location is crucial for selecting the appropriate treatment for the patient. Treatment options include medical management, interventional radiology and surgery, depending on the patient's symptoms and fertility desires. EVIDENCE SYNTHESIS: Gynecologists must create personalized plans based on fibroid characteristics and their potential impact on fertility. Hysteroscopic myomectomy has been shown to improve pregnancy rates in certain cases. However, myomectomy is not always recommended for asymptomatic women with fibroids that do not distort the uterine cavity. It may be considered when pelvic anatomy is significantly affected, because it hinders procedures like oocyte retrieval. The relationship between specific number, size and position of myomas (excluding submucosal myomas or intramural myomas that distort the endometrial cavity) with the outcomes of pregnancy has not been verified.

conclusionConsidering the lack of current randomized controlled trials (RCTs) investigating the effects of myomectomy, it is advisable to conduct future multicenter prospective studies.

Identifiers

PMID39974436
PMCPMC11834833

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.