Evidence map›Paper›PMID 39974433›Full record

ArticleMaedica2024

How Effective is Ozone Therapy in Treatment of Lumbar Disc Disease: a Systematic Review of Prospective Studies.

Vishal Kumar, Syed Ifthekar, Vikash Raj, Seshadri Reddy Varikasuvu, Aakash Jain, Arvind Vatkar, Pankaj Kandwal, Sitanshu Barik

Abstract readEditorial
PubMed Full text at PMC Publisher
In one paragraph

Article in Maedica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vishal KumarAdditional Professor, Orthopedics, PGIMER, Chandigarh, India.
Syed IfthekarAssistant Professor, Orthopedics, All India Institute of Medical Sciences, Bibinagar, India.
Vikash RajAssociate Professor, Orthopedics, All India Institute of Medical Sciences, Deoghar, India.
Seshadri Reddy VarikasuvuAssociate Professor, Biochemistry, All India Institute of Medical Sciences,Deoghar, India.
Aakash JainSenior Resident, Orthopedics, All India Institute of Medical Sciences, Rishikesh, India.
Arvind VatkarConsultant, Orthopedics, Apollo Hospitals, Mumbai, India.
Pankaj KandwalHead, Orthopedics, All India Institute of Medical Sciences, Rishikesh, India.
Sitanshu BarikAssociate Professor, Orthopedics, All India Institute of Medical Sciences, Nagpur, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWith numerous studies reporting on the clinical efficacy of ozone therapy, there has been a growing interest in its use for disc herniation in lumbar disc disease. The aim of this meta-analysis is to explore the results of the prospective studies using ozone for the treatment of lumbar disc disease.

methodsOnline electronic databases of PubMed, Embase and Scopus were searched using relevant keywords. This review included prospective studies on the treatment of lumbar disc herniation using ozone therapy.

resultsA mean improvement of 4.25 (95% CI 2.93-5.58) in visual analogue scale (VAS) scores was noted. A mean improvement of 20.57 (95% CI 18.47-22.68) in Oswestry disability index (ODI) was noted across the studies on meta-analysis. Meta-regression of the pre-operative and post-operative VAS score did not show any significant association with age at procedure, gender or the level of lumbar disc disease. None of the selected studies reported any minor or major complication.

conclusionOzone treatment in low back pain associated with herniated disc is an effective therapy and can be considered as a standard treatment in cases which failed for conservative treatment. Ozone therapy is a simple method and can be effectively delivered with minimal adverse effects. However, additional meta-analysis with high quality randomised controls can be done to further strengthen the evidence for this mode of treatment.

Identifiers

PMID39974433
PMCPMC11834825

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