Evidence map›Paper›PMID 39974315›Full record

ReviewRSC advances2025

Recent advances on anticancer activity of benzodiazine heterocycles through kinase inhibition.

Mohamed S Nafie, Sherif Ashraf Fahmy, Shaima H Kahwash, Mohamed K Diab, Kamal M Dawood, Ashraf A Abbas

Abstract readReview
In one paragraph

Review in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Synthesis and Biological Activity of Azolo[Molecules (Basel, Switzerland) · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohamed S NafieDepartment of Chemistry, College of Sciences, University of Sharjah Sharjah 27272 United Arab Emirates mohamed.elsayed@sharjah.ac.ae.ORCID https://orcid.org/0000-0003-4454-6390
Sherif Ashraf FahmyDepartment of Pharmaceutics and Biopharmaceutics, University of Marburg Robert-Koch-Str. 4 35037 Marburg Germany.ORCID https://orcid.org/0000-0003-3056-8281
Shaima H KahwashDepartment of Chemistry, Faculty of Science, Suez Canal University Ismailia 41522 Egypt mohamed_nafie@science.suez.edu.eg.
Mohamed K DiabPest Physiology Department, Plant Protection Research Institute, Agricultural Research Center Giza 12311 Egypt.ORCID https://orcid.org/0000-0001-7879-1357
Kamal M DawoodChemistry Department, Faculty of Science, Cairo University Giza 12613 Egypt.ORCID https://orcid.org/0000-0002-1351-9886
Ashraf A AbbasChemistry Department, Faculty of Science, Cairo University Giza 12613 Egypt.ORCID https://orcid.org/0000-0001-7061-9907

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The benzodiazines (phthalazine, quinazoline, quinoxaline, and cinnoline) have emerged as attractive scaffolds for creating novel anticancer drugs. These nitrogen-containing heterocycles are intriguing because they have a variety of configurations and can change chemically, allowing us to tailor their pharmacokinetic and pharmacodynamic features. Numerous studies have found that derivatives of these compounds have potent anticancer properties

Identifiers

PMID39974315
PMCPMC11836603

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.