ArticleEuropean heart journal. Imaging methods and practice2025
Noninvasive assessment of myocardial perfusion using ultrafast ultrasound: clinical study for congenital heart disease.
Article in European heart journal. Imaging methods and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07361523 (Using Near-Infrared Spectroscopy Devices to Assess Myocardial and Visceral Perfusion During Complex Congenital Cardiac Surgery), which is not on this map. Not yet cited in PubMed.
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Using Near-Infrared Spectroscopy Devices to Assess Myocardial and Visceral Perfusion During Complex Congenital Cardiac Surgery
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8 authors.
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Abstract
Aims: Myocardial perfusion impacts cardiac function following surgical repair of critical congenital heart disease (CCHD). Temporal variation assessment of myocardial blood volume throughout the cardiac cycle can be a surrogate for perfusion. Ultrafast power Doppler (UPD) is an ultrasound imaging technique capable of noninvasively quantifying myocardial blood volume changes. The objective of this study is to demonstrate the feasibility of perioperative transthoracic UPD assessment and to determine if UPD reflects physiologic changes in myocardial perfusion. Methods and results: Five neonatal transposition of the great arteries (TGA) undergoing arterial switch operation (ASO), five hypoplastic left heart syndrome (HLHS) undergoing Stage 1 palliation (S1P), and five age/weight-matched controls were prospectively recruited. Transthoracic UPD acquisitions were performed before/after operations. Segmental perfusion in right/left ventricles (RV/LV) was assessed. The controls' myocardial perfusion patterns are visually similar to published human references for both ventricles. Systolic/diastolic myocardial perfusion differences were modified by ASO in the RV ( Conclusion: For TGA patients, the perfusion profile of the myocardium seems to be directly influenced by the intracavitary pressure (directly driving coronary perfusion pressure), namely if it was the systemic or sub-pulmonary ventricle. Our data suggests that UPD could noninvasively quantify myocardial perfusion variation. Myocardial perfusion patterns change in CCHD according to their haemodynamic and surgical status. Correlation with clinical outcomes requires further study.
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