ReviewCureus2025
Orbital Abscesses: A Systematic Review of Clinical Presentation, Diagnostic Tools, and Treatment Modalities.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Ocular Abscess Causing Remarkable Eyeball Deformity.Internal medicine (Tokyo, Japan) · 2026Article
- Article
- Neurosurgical robot-assisted transnasal endoscopic surgery in orbital-related diseases.Brain & spine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Orbital abscesses, though rare, represent a serious complication of sinusitis and can result in significant morbidity, including permanent vision loss and intracranial spread if not managed promptly. This systematic review aims to provide a detailed analysis of the clinical presentation, diagnostic modalities, treatment approaches, and outcomes in patients with orbital abscesses. This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A comprehensive literature search was conducted across PubMed and Scopus, yielding 19 studies involving 36 patients with orbital abscesses. Data extraction focused on study design, sample size, patient demographics (age, gender), clinical presentation, diagnostic tools, treatment modalities, and outcomes, including resolution rates, complications, and recurrence. Orbital abscesses primarily affected younger populations, with a mean patient age of nine years. The most common symptoms solicited were proptosis at 75%, periorbital swelling at 80%, and pain at 70%. The diagnostic modality used in the majority, 89%, was imaging with computed tomography. All cases were given empiric intravenous antibiotics and third-generation cephalosporins, with added metronidazole. Of all the patients, 44% had to undergo any surgical intervention, usually in cases of larger abscesses or where the optic nerve was implicated. Endoscopic sinus surgery (ESS) was the most frequently used surgical approach, with a high success rate. A total of 78% of patients achieved complete resolution, and 80% experienced improved visual acuity. However, delayed intervention led to permanent vision loss in 5.5% of cases, highlighting the importance of timely treatment. The median hospital stay ranged from one to two weeks, depending on the severity of the condition and the treatment modality. Managing an orbital abscess requires early detection and treatment to avoid complications like loss of vision and intracranial extension. Smaller, medially located abscesses can be effectively treated with conservative antibiotic therapy, while larger or complicated cases require surgical treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.