Evidence map›Paper›PMID 39974157›Full record

ArticleFrontiers in veterinary science2025

Evaluation of twin-arginine translocation substrate proteins as potential antigen candidates for serodiagnosis of brucellosis.

Yao Wu, Xin Yan, Mingjun Sun, Xiaohan Guo, Jiaqi Li, Xiangxiang Sun, Mengda Liu, Haobo Zhang, Wenlong Nan, Weixing Shao and 3 more

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yao Wu *Laboratory of Zoonoses, China Animal Health and Epidemiology Center, Qingdao, China.
Xin Yan *Laboratory of Zoonoses, China Animal Health and Epidemiology Center, Qingdao, China.
Mingjun SunLaboratory of Zoonoses, China Animal Health and Epidemiology Center, Qingdao, China.
Xiaohan GuoKey Lab of Environment and Health, School of Public Health, Xuzhou Medical University, Xuzhou, China.
Jiaqi LiLaboratory of Zoonoses, China Animal Health and Epidemiology Center, Qingdao, China.
Xiangxiang SunLaboratory of Zoonoses, China Animal Health and Epidemiology Center, Qingdao, China.
Mengda LiuLaboratory of Zoonoses, China Animal Health and Epidemiology Center, Qingdao, China.
Haobo ZhangLaboratory of Zoonoses, China Animal Health and Epidemiology Center, Qingdao, China.
Wenlong NanLaboratory of Zoonoses, China Animal Health and Epidemiology Center, Qingdao, China.
Weixing ShaoLaboratory of Zoonoses, China Animal Health and Epidemiology Center, Qingdao, China.
Fangkun WangCollege of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an, China.
Xiaoxu FanLaboratory of Zoonoses, China Animal Health and Epidemiology Center, Qingdao, China.
Shufang SunLaboratory of Zoonoses, China Animal Health and Epidemiology Center, Qingdao, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Brucellosis, an infectious zoonotic disease caused by members of the genus Methods: In this study, ErfK, YxeI, and EntF were expressed in prokaryotic cells and utilized as diagnostic antigens. The clinical sera from bovines and sheep diagnosed with brucellosis were analyzed using indirect ELISA with these proteins. Results: For bovine serum, the combined protein group (ErfK + YxeI + EntF) and YxeI demonstrated the highest diagnostic accuracy of 94.23% and 93.58%, respectively. Meanwhile, the combined protein group showed the strongest ability to detect Conclusion: The findings of this study suggest that Tat substrate proteins serve as promising candidate antigens with significant potential value for the clinical diagnosis of brucellosis.

Indexed as

BrucelladiagnosisELISAtranslocated substratestwin-arginine protein translocation

Identifiers

PMID39974157
PMCPMC11836645

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.