Evidence map›Paper›PMID 39974131›Full record

ArticlemedRxiv : the preprint server for health sciences2025

Fusion oncoproteins and cooperating mutations define disease phenotypes in

Masayuki Umeda, Ryan Hiltenbrand, Nicole L Michmerhuizen, Juan M Barajas, Melvin E Thomas, Bright Arthur, Michael P Walsh, Guangchun Song, Jing Ma, Tamara Westover and 17 more

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

27 authors.

Masayuki UmedaDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, US.
Ryan HiltenbrandDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, US.
Nicole L MichmerhuizenDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, US.
Juan M BarajasDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, US.
Melvin E ThomasDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, US.
Bright ArthurDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, US.
Michael P WalshDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, US.
Guangchun SongDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, US.
Jing MaDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, US.
Tamara WestoverDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, US.
Amit KumarCenter of Excellence for Leukemia Studies (CELS), St. Jude Children's Research Hospital, Memphis, TN, US.
Petri PölönenDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, US.
Cristina MecucciDepartment of Medicine and Surgery, Hematology and Bone Marrow Transplantation Unit, University of Perugia, Perugia, Italy.
Danika Di GiacomoDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, US.
Franco LocatelliDepartment of Onco-Haematology and Cell and Gene Therapy, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Riccardo MasettiPediatric Oncology and Hematology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Salvatore N BertuccioIRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Martina PigazziDepartment of Women's and Children's Health, Onco-hematology lab and clinic, University of Padova, Padova, Italy.
Shondra M Pruett-MillerCenter for Advanced Genome Engineering, St. Jude Children's Research Hospital, Memphis, TN, US.
Stanley PoundsDepartment of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, US.
Jeffrey RubnitzDepartment of Oncology, St. Jude Children's Research Hospital, Memphis, TN, US.
Hiroto InabaDepartment of Oncology, St. Jude Children's Research Hospital, Memphis, TN, US.
Kyriakos P PapadopoulosXenoSTART/ The START Center for Cancer Research, San Antonio, TX, US.
Michael J WickXenoSTART/ The START Center for Cancer Research, San Antonio, TX, US.
Ilaria IacobucciDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, US.
Charles G MullighanDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, US.
Jeffery M KlcoDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, US.

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Shondra Michelle Miller · 1985 to 2026
$166.9M
Translating genomic discoveries to improved outcomes for high risk acute leukemiaR35CA197695 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Charles G Mullighan · 2017 to 2026
$11.4M
Project 4U54CA243124 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI MULLIGHAN, CHARLES G. · 2019 to 2023
$10.5M
UBTF Tandem Duplications in Pediatric Acute Myeloid LeukemiaR01CA276079 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Jeffery M Klco · 2023 to 2026
$1.6M
NCI NIH HHS P30 CA021765NCI NIH HHS R01 CA276079NCI NIH HHS R35 CA197695NCI NIH HHS U54 CA243124
6 · The paper itself

Abstract

Leukemias with

Identifiers

PMID39974131
PMCPMC11838931

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.