ReviewChem & bio engineering2024
Review on Blood Flow Dynamics in Lab-on-a-Chip Systems: An Engineering Perspective.
Review in Chem & bio engineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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Who cites it
4 citing papers in PubMed.
- Micro Blood Flow-Resolved Rheometry.Micromachines · 2026Article
- A two-phase core-plasma model for microvascular blood flow: Comparative analysis of hemodynamic models.PloS one · 2026Article
- Intelligent Microfluidics for Plasma Separation: Integrating Computational Fluid Dynamics and Machine Learning for Optimized Microchannel Design.Biosensors · 2025Article
- Optimization of Microfluidics for Point-of-Care Blood Sensing.Biosensors · 2024Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Under different transport mechanisms, blood flow dynamics, heavily linked to the flow shear rate conditions, in "lab-on-a-chip" (LOC) systems are found to result in varying transport phenomena. This Review examines the blood flow patterns in LOC systems through the role of viscoelastic properties such as dynamic blood viscosity and elastic behavior of the red blood cells. The study of blood transport phenomena in LOC systems through key parameters of capillary and electro-osmotic forces is provided through experimental, theoretical, and numerous numerical approaches. The disturbance triggered by electro-osmotic viscoelastic flow is particularly discussed and applied in the enhancement of the mixing and separating capabilities of LOC devices handling blood and other viscoelastic fluids for future research opportunities. Furthermore, the Review identifies the challenges in the numerical modeling of blood flow dynamics under the LOC systems, such as the call for more accurate and simplified blood flow models and the emphasis on numerical studies of viscoelastic fluid flow under the electrokinetic effect. More practical assumptions for zeta potential conditions while studying the electrokinetic phenomena are also highlighted. This Review aims to provide a comprehensive and interdisciplinary perspective on blood flow dynamics in microfluidic systems driven by capillary and electro-osmotic forces.
Identifiers
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Registered trials
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