Evidence map›Paper›PMID 39973927›Full record

ArticleFrontiers in microbiology2025

Comprehensive analysis of lncRNAs and mRNAs revealed potential participants in the process of avian reovirus infection.

Shaqiu Zhang, Jinkang Li, Mingshu Wang, Renyong Jia, Shun Chen, Mafeng Liu, Dekang Zhu, Xinxin Zhao, Ying Wu, Qiao Yang and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Animal virus-host interactions mediated by non-coding RNAs.Frontiers in cellular and infection microbiology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Shaqiu Zhang *Avian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Jinkang Li *Avian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Mingshu WangAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Renyong JiaAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Shun ChenAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Mafeng LiuAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Dekang ZhuAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Xinxin ZhaoAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Ying WuAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Qiao YangAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Juan HuangAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Xumin OuAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Di SunAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Bin TianAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Yu HeAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Zhen WuAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
Anchun ChengAvian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Avian reovirus (ARV), a double-stranded RNA virus, frequently induces immunosuppression in poultry, leading to symptoms such as irregular bleeding and spleen necrosis in infected ducks. Since 2017, the morbidity and mortality rates associated with ARV infection in poultry have been on the rise, progressively emerging as a significant viral disease impacting the duck farming industry in China. In our study, we collected duck embryo fibroblasts 18 h post-infection with ARV and conducted transcriptome sequencing analysis. The analysis revealed that 3,818 mRNA expressions were up-regulated, 4,573 mRNA expressions were down-regulated, 472 long noncoding RNAs (LncRNAs) were up-regulated, and 345 lncRNAs were down-regulated. We employed qRT-PCR to validate the sequencing results, confirming their accuracy. The transcriptome data indicated significant upregulation of the

Indexed as

avian reovirusavian reovirus replicationlinc000889long noncoding RNAtranscriptome sequencing

Identifiers

PMID39973927
PMCPMC11835999

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.