ReviewJournal of neonatal-perinatal medicine2025
Surgical NEC-associated cerebellar underdevelopment and PDA: Call for close monitoring and action.
Review in Journal of neonatal-perinatal medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- The association between patent ductus arteriosus and adverse outcomes in preterm infants.BMC pediatrics · 2026Article
- Clinical Impact of the PDA and Its Management on Outcomes of Preterm Infants with NEC: A Review.American journal of perinatology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Necrotizing enterocolitis (NEC) is a systemic inflammatory disease of very low birth weight infants and is associated with brain injury and poor neurodevelopmental outcomes. The cerebellar injury is seen in one third of cases with surgical cases. The association between patent ductus arteriosus (PDA) and necrotizing enterocolitis, cerebral and gut hemodynamics in preterm infants is well documented. The cerebellum is at the high risk of underdevelopment and injury in preterm infants with surgical NEC and PDA. The combined exposure of NEC and PDA most likely affect the normal cerebellar development further due to inflammatory and hypoperfusion insults. There is a need to develop the targeted monitoring and therapeutic approach for cerebellum in preterm infants with surgical NEC and PDA.
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Registered trials
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