Evidence map›Paper›PMID 39973505›Full record

ArticleJournal of Parkinson's disease2025

Improving reliability of movement assessment in Parkinson's disease using computer vision-based automated severity estimation.

Jinyu Xu, Xin Xu, Xudong Guo, Zezhi Li, Boya Dong, Chen Qi, Chunhui Yang, Dong Zhou, Jiali Wang, Lu Song and 13 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of Parkinson's disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Jinyu XuChanghai Hospital, Shanghai, China.
Xin XuChinese PLA General Hospital First Medical Center, Beijing, China.
Xudong GuoAffiliated Brain Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Zezhi LiAffiliated Brain Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Boya DongNERVTEX Co. Ltd, Shanghai, China.
Chen QiXinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Chunhui YangChanghai Hospital, Shanghai, China.ORCID 0000-0002-0532-1060
Dong ZhouNERVTEX Co. Ltd, Shanghai, China.
Jiali WangChanghai Hospital, Shanghai, China.
Lu SongXinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0000-0002-4742-7816
Ping HeChinese PLA General Hospital First Medical Center, Beijing, China.
Shanshan KongChinese PLA General Hospital First Medical Center, Beijing, China.
Shuchang ZhengAffiliated Brain Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Sichao FuNERVTEX Co. Ltd, Shanghai, China.
Wei XieChinese PLA General Hospital First Medical Center, Beijing, China.
Xuan LiuNERVTEX Co. Ltd, Shanghai, China.
Ya CaoChinese PLA General Hospital First Medical Center, Beijing, China.
Yilin LiuNERVTEX Co. Ltd, Shanghai, China.
Yiqing QiuChanghai Hospital, Shanghai, China.ORCID 0000-0002-5212-1117
Zhiyuan ZhengHainan Hospital of People's Liberation Army General Hospital, Sanya, Hainan, China.
Fei YangChinese PLA General Hospital First Medical Center, Beijing, China.
Jing GanXinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0000-0002-1893-1132
Xi WuChanghai Hospital, Shanghai, China.ORCID 0000-0002-1248-3420

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundClinical assessments of motor symptoms rely on observations and subjective judgments against standardized scales, leading to variability due to confounders. Improving inter-rater agreement is essential for effective disease management.ObjectiveWe developed an objective rating system for Parkinson's disease (PD) that integrates computer vision (CV) and machine learning to correct potential discrepancies among raters while providing the basis for model performance to gain professional acceptance.MethodsA prospective PD cohort (n = 128) were recruited from multi-centers. Motor examination videos were recorded using an android tablet with CV-based software following the MDS-UPDRS Part-III instructions. Videos included facial, upper- and lower-limb movements, arising from a chair, standing, and walking. Fifteen certified clinicians were recruited from multi-centers. For each video, five clinicians were randomly selected to independently rate the severity of motor symptoms, validate the videos and movement variables (MovVars). Machine learning algorithms were applied for automated rating and feature importance analysis. Inter-rater agreement among human raters and the agreement between artificial intelligence (AI)-generated ratings and expert consensus were calculated.ResultsFor all validated videos (n = 1024), AI-based ratings showed an average absolute accuracy of 69.63% and an average acceptable accuracy of 98.78% against the clinician consensus. The mean absolute error between the AI-based scores and clinician consensus was 0.32, outperforming the inter-rater variability (0.65), potentially due to the combined utilization of diverse MovVars.ConclusionsThe algorithm enabled accurate video-based evaluation of mild motor symptom severity. AI-assisted assessment improved the inter-rater agreement, demonstrating the practical value of CV-based tools in screening, diagnosing, and treating movement disorders.

Indexed as

Machine LearningNeurologic ExaminationParkinson DiseaseSeverity of Illness IndexAgedFemaleHumansMaleMiddle AgedMovementProspective StudiesReproducibility of ResultsVideo Recordingartificial intelligencecomputer visionmachine learningMDS-UPDRS IIIParkinson's diseasevideo

Identifiers

PMID39973505
PMCPMC13347443

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.