Evidence map›Paper›PMID 39973175›Full record

ArticleFuture oncology (London, England)2025

Epidemiology, resource use, and treatment patterns of locally advanced or metastatic urothelial carcinoma in France.

Florence Joly, Stephane Culine, Morgan Roupret, Aurore Tricotel, Emilie Casarotto, Sandrine Brice, Rafael Minacori, Marthe Vuillet, Marie-Catherine Thomas, Kirsten Leyland and 3 more

Abstract read
In one paragraph

Article in Future oncology (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Florence JolyINSERM, U1086 ANTICIPE, Normandie University, UNICAEN, Caen, France.
Stephane CulineDepartment of Medical Oncology, Hôpital Saint-Louis, AP-HP, Paris, France.
Morgan RoupretGRC 5 Predictive Onco-Uro, AP-HP, Urology, Pitié-Salpêtrière Hospital, Sorbonne University, Paris, France.
Aurore TricotelReal World Evidence Solutions, IQVIA, La Défense Cedex, France.
Emilie CasarottoReal World Evidence Solutions, IQVIA, La Défense Cedex, France.
Sandrine BriceReal World Evidence Solutions, IQVIA, La Défense Cedex, France.
Rafael MinacoriAstellas Pharma, Levallois-Perret, France.
Marthe VuilletAstellas Pharma, Levallois-Perret, France.
Marie-Catherine ThomasAstellas Pharma, Levallois-Perret, France.
Kirsten LeylandAstellas Pharma Europe, Addlestone, UK.
Anil UpadhyayAstellas Pharma Europe, Addlestone, UK.
Vicki MunroAstellas Pharma Europe, Addlestone, UK.
Torsten Strunz-McKendryAstellas Pharma Europe, Addlestone, UK.ORCID 0000-0001-6032-8794

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimDescribe real-world epidemiology, treatment patterns, health care resource utilization, and costs of locally advanced or metastatic urothelial carcinoma (la/mUC) in France. PATIENTS &

methodsRetrospective study including all adults with la/mUC diagnosis during January 2017 to December 2020 in the PMSI database.

resultsAnnual prevalence and incidence ranged from 36.4 to 38.9 and 16.4 to 18.5 cases per 100,000 people, respectively. Of the 25,314 patients with incident la/mUC, 37.6% did not receive first-line systemic treatment. Of the 14,656 patients who started first-line systemic treatment, 66.6%, 22.5%, and 10.9% received 1, 2, and 3 lines of therapy, respectively. Annual per-patient costs in second-/third-line setting ranged from €8803 to €16,012.

conclusionThe substantial disease burden of la/mUC in France highlights the unmet need for new therapies.

Indexed as

Carcinoma, Transitional CellHealth ResourcesUrinary Bladder NeoplasmsAdultAgedAged, 80 and overFemaleFranceHealth Care CostsHumansIncidenceMaleMiddle AgedNeoplasm MetastasisPrevalenceRetrospective StudiescostsFranceIncidenceprevalencetreatmenturothelial carcinoma

Identifiers

PMID39973175
PMCPMC11881851

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.