Evidence map›Paper›PMID 39973139›Full record

ArticleZoological research2025

Whole-genome sequencing reveals genetic architecture and selection signatures of Kazakh cattle.

Zhannur Niyazbekova, Yuan Xu, Min Qiu, Hao-Ping Wang, Ibragimov Primkul, Hojjat Asadollahpour Nanaei, Yessengali Ussenbekov, Kuanysh Kassen, Yi Liu, Cai-Yue Gao and 4 more

Abstract read
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Article in Zoological research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Zhannur NiyazbekovaCollege of Animal Science and Technology, Northwest A & F University, Yangling, Shaanxi 712100, China.
Yuan XuCollege of Animal Science and Technology, Northwest A & F University, Yangling, Shaanxi 712100, China.
Min QiuCollege of Animal Science and Technology, Northwest A & F University, Yangling, Shaanxi 712100, China.
Hao-Ping WangCollege of Animal Science and Technology, Northwest A & F University, Yangling, Shaanxi 712100, China.
Ibragimov PrimkulFaculty of Veterinary Medicine, Kazakh National Agrarian Research University, Almaty 050000, Kazakhstan.
Hojjat Asadollahpour NanaeiCollege of Animal Science and Technology, Northwest A & F University, Yangling, Shaanxi 712100, China.
Yessengali UssenbekovFaculty of Veterinary Medicine, Kazakh National Agrarian Research University, Almaty 050000, Kazakhstan.
Kuanysh KassenCollege of Plant Protection, Northwest A & F University, Yangling, Shaanxi 712100, China.
Yi LiuInstitute of Animal Husbandry and Veterinary Science, Tianjin Academy of Agricultural Sciences, Tianjin 300381, China.
Cai-Yue GaoCollege of Animal Science and Technology, Northwest A & F University, Yangling, Shaanxi 712100, China.
Shynar AkhmetsadykovaResearch and Production Enterprise "ANTIGEN" Co. Ltd., Abai Village, Almaty 050409, Kazakhstan.
Nuriddin RuzikulovSamarkand State University of Veterinary Medicine, Animal Husbandry and Biotechnology, Samarkand 140103, Uzbekistan.
Yu JiangCollege of Animal Science and Technology, Northwest A & F University, Yangling, Shaanxi 712100, China. E-mail: yu.jiang@nwafu.edu.cn.
Yu-Dong CaiCollege of Animal Science and Technology, Northwest A & F University, Yangling, Shaanxi 712100, China. E-mail: yudong.cai@nwafu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Local cattle breeds play a critical role in breeding programs due to their genetic adaptations to diverse environmental conditions. However, the genomic architecture of local cattle breeds in Kazakhstan remains largely unexplored. This study utilized whole-genome sequencing data from Kazakh cattle to elucidate their genetic composition, uncovering three primary ancestral components: European, Eurasian, and East Asian taurine. The East Asian taurine lineage likely represents the earliest genetic contribution to Kazakh cattle but was largely replaced by subsequent waves of cattle migrations across Eurasia, leaving only a minor genetic signature in the current cattle population. In contrast, Eurasian taurine ancestry predominated in the Alatau and Kazakh local breeds, while the European taurine component was most prevalent in Kazakh white-headed cattle, consistent with their documented breeding history. Kazakh cattle exhibited higher genetic diversity and lower inbreeding coefficients compared to European commercial breeds, reflecting reduced exposure to intense artificial selection. A strong selection signal was identified on chromosome 6 at a locus encompassing

Indexed as

Genetic VariationGenomeSelection, GeneticWhole Genome SequencingAnimalsBreedingCattleKazakhstanAlatau cattleGenetic diversityKazakh white-headed cattleLocal breedSelection signatures.Whole-genome sequencing

Identifiers

PMID39973139
PMCPMC12000138

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.