Evidence map›Paper›PMID 39973068›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Peptide Multifunctionalization via Modular Construction of Trans-AB

Yue Wu, Yuen-Ting Wong, Yik-Hoi Yeung, Pak-Lun Lam, Ho-Fai Chau, Wing-Sze Tam, Qian Zhang, William C S Tai, Ka-Leung Wong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Peptide Multifunctionalization via Modular Construction of Trans-ABAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yue WuDepartment of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, 11 Yuk Choi Rd, Hung Hom, Hong Kong, SAR, China.ORCID https://orcid.org/0000-0001-7296-8182
Yuen-Ting WongDepartment of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, 11 Yuk Choi Rd, Hung Hom, Hong Kong, SAR, China.
Yik-Hoi YeungDepartment of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, 11 Yuk Choi Rd, Hung Hom, Hong Kong, SAR, China.ORCID https://orcid.org/0000-0001-8446-4694
Pak-Lun LamDepartment of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, 11 Yuk Choi Rd, Hung Hom, Hong Kong, SAR, China.ORCID https://orcid.org/0000-0002-3558-7855
Ho-Fai ChauDepartment of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, 11 Yuk Choi Rd, Hung Hom, Hong Kong, SAR, China.ORCID https://orcid.org/0000-0001-6964-1840
Wing-Sze TamDepartment of Chemistry, Hong Kong Baptist University, 224 Waterloo Rd, Kowloon Tong, Hong Kong, SAR, China.ORCID https://orcid.org/0000-0002-9288-0804
Qian ZhangDepartment of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, 11 Yuk Choi Rd, Hung Hom, Hong Kong, SAR, China.
William C S TaiDepartment of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, 11 Yuk Choi Rd, Hung Hom, Hong Kong, SAR, China.ORCID https://orcid.org/0000-0002-0771-7894
Ka-Leung WongDepartment of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, 11 Yuk Choi Rd, Hung Hom, Hong Kong, SAR, China.ORCID https://orcid.org/0000-0002-3750-5980

Funding

Centre for Medical Engineering of Molecular and Biological Probes AoE/M-401/20NSFC/RGC Joint Research Scheme N_PolyU209/21Research Grants Council, University Grants Committee 12300021
6 · The paper itself

Abstract

Peptide multifunctionalization is a crucial technique to develop peptide-based agents for various purposes. Porphyrin-peptide conjugates are a class of popular multifunctional peptides renowned for their multifunctional and multimodal properties. However, the tedious synthetic works for porphyrin building blocks are involved in most previous studies. In this work, a modular solid-phase synthetic approach is reported to construct trans-AB

Indexed as

PeptidesPorphyrinsSolid-Phase Synthesis TechniquesPeptidesPorphyrinsmultifunctional peptidepeptide ligationporphyrinporphyrin‐peptide conjugatessolid‐phase peptide synthesis

Identifiers

PMID39973068
PMCPMC11984925

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.