Evidence map›Paper›PMID 39972712›Full record

ArticleJACC. Case reports2025

Neoadjuvant Combined Preoperative Embolization of a Highly Vascularized Paraganglioma Associated With SIADH.

Maria Felicia Gagliardi, Edoardo Cantù, Gianluca Tiberti, Alberto Clerici, Andrea Galanti, Andrea Farina, Antonio Cappello, Giovanni Leati, Giuseppe Verolino, Michele Triggiani

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maria Felicia GagliardiSchool of Medicine and Surgery, Milano-Bicocca University, Milan, Italy.
Edoardo CantùDepartment of Cardiac, Thoracic, Vascular Sciences, Alessandro Manzoni Hospital, ASST Lecco, Lecco, Italy; Department of Cardiology, S. Leopoldo Mandic, ASST Lecco, Lecco, Italy.
Gianluca TibertiDepartment of Cardiac, Thoracic, Vascular Sciences, Alessandro Manzoni Hospital, ASST Lecco, Lecco, Italy.
Alberto ClericiDepartment of Cardiac, Thoracic, Vascular Sciences, Alessandro Manzoni Hospital, ASST Lecco, Lecco, Italy.
Andrea GalantiDepartment of Cardiac, Thoracic, Vascular Sciences, Alessandro Manzoni Hospital, ASST Lecco, Lecco, Italy.
Andrea FarinaDepartment of Cardiac, Thoracic, Vascular Sciences, Alessandro Manzoni Hospital, ASST Lecco, Lecco, Italy.
Antonio CappelloDepartment of Diagnostic Imaging, Alessandro Manzoni Hospital, ASST Lecco, Lecco, Italy.
Giovanni LeatiDepartment of Diagnostic Imaging, Alessandro Manzoni Hospital, ASST Lecco, Lecco, Italy.
Giuseppe VerolinoInvasive Cardiology, Department of Cardiology, IRCCS Istituto Auxologico Italiano, Milan, Italy. Electronic address: g.verolino@auxologico.it.
Michele TriggianiDepartment of Cardiac, Thoracic, Vascular Sciences, Alessandro Manzoni Hospital, ASST Lecco, Lecco, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDevice-based embolization is a well-established medical procedure for treating several pathological conditions, including cerebral and peripheral pseudoaneurysms, congenital defects, and active bleeding. Nonetheless, an intriguing and relatively underexplored application of coils and microparticles involves the preoperative reduction of blood supply to ectopic masses. CASE SUMMARY: A 58-year-old woman was admitted to our institution with nausea and confusion, with a suspected diagnosis of syndrome of inappropriate antidiuretic hormone secretion. A computed tomography scan revealed a large mediastinal mass receiving blood supply from both the bronchial and coronary arteries. The mass was successfully excised surgically, following the embolization of the major feeding vessels using a combination of coils and microspheres. DISCUSSION: An uncommon presentation of a paraganglioma characterized by both mass effect and endocrine activity required a "neoadjuvant" treatment to ensure safer surgical management. TAKE-HOME MESSAGE: The percutaneous reduction of blood supply to tumoral mass could represent an effective strategy to guarantee a radical excision without major complications.

Indexed as

cancercardiovascular diseasecomputed tomographycoronary angiographypercutaneous coronary interventionthoracotomy

Identifiers

PMID39972712
PMCPMC11862302

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.