Evidence map›Paper›PMID 39972674›Full record

ArticleThe Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology2025

Monotropein resists atherosclerosis by reducing inflammation, oxidative stress, and abnormal proliferation and migration of vascular smooth muscle cells.

Hongliang Li, Bingqian Ye, Jiping Tian, Bofan Wang, Yiwen Zha, Shuying Zheng, Tan Ma, Wenwen Zhuang, Won Sun Park, Jingyan Liang

Abstract read
In one paragraph

Article in The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. What KJPP looks for: guidance from initial editorial screening.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hongliang LiInstitute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225001, Jiangsu, China.
Bingqian YeInstitute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225001, Jiangsu, China.
Jiping TianInstitute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225001, Jiangsu, China.
Bofan WangInstitute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225001, Jiangsu, China.
Yiwen ZhaInstitute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225001, Jiangsu, China.
Shuying ZhengInstitute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225001, Jiangsu, China.
Tan MaInstitute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225001, Jiangsu, China.
Wenwen ZhuangDepartment of Physiology, Kangwon National University School of Medicine, Chuncheon 24341, Korea.
Won Sun ParkInstitute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225001, Jiangsu, China.
Jingyan LiangInstitute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225001, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monotropein is a compound classified into iridoid which is found in herbaceous plants Morindae officinalis. It possesses anti-inflammatory, antioxidant, and anti-osteoarthritic activities. Previous study indicates that monotropein may have the potential to combat cardiovascular disease, although the related mechanism remains unclear. In this study, we constructed the model of atherosclerosis by oxidized low density lipoprotein-induced vascular smooth muscle cells and LDLR

Indexed as

AtherosclerosisMigrationMonotropeinProliferationVascular smooth muscle

Identifiers

PMID39972674
PMCPMC11842295

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.