Evidence map›Paper›PMID 39972563›Full record

ArticleJournal of sleep research2025

Weather-Associated Variations of Device-Detected Severe Sleep Apnea in Cardiac Pacemaker Patients.

Valentin Bilgeri, Philipp Spitaler, Patrick Rockenschaub, Fabian Lehner, Bernhard Erich Pfeifer, Peter Willeit, Fabian Barbieri, Ambra Stefani, Birgit Högl, Herbert Formayer and 2 more

Abstract read
In one paragraph

Article in Journal of sleep research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Valentin BilgeriDepartment of Internal Medicine III, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0009-0006-4889-2177
Philipp SpitalerDepartment of Internal Medicine III, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0002-5908-2923
Patrick RockenschaubInstitute of Clinical Epidemiology, Public Health, Health Economics, Medical Statistics and Informatics, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0002-6499-7933
Fabian LehnerInstitute of Meteorology and Climatology, BOKU University, Vienna, Austria.
Bernhard Erich PfeiferLandesinstitut für integrierte Versorgung Tirol, Tirol Kliniken, Innsbruck, Austria.
Peter WilleitInstitute of Clinical Epidemiology, Public Health, Health Economics, Medical Statistics and Informatics, Medical University of Innsbruck, Innsbruck, Austria.
Fabian BarbieriDepartment of Cardiology, Angiology and Intensive Care, Deutsches Herzzentrum der Charité, Berlin, Germany.ORCID 0000-0003-4456-1822
Ambra StefaniDepartment of Neurology, Center for Sleep Medicine, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0003-4259-8824
Birgit HöglDepartment of Neurology, Center for Sleep Medicine, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0003-1894-7641
Herbert FormayerInstitute of Meteorology and Climatology, BOKU University, Vienna, Austria.ORCID 0000-0002-2126-9696
Axel BauerDepartment of Internal Medicine III, Medical University of Innsbruck, Innsbruck, Austria.
Wolfgang DichtlDepartment of Internal Medicine III, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0002-0421-2110

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Using continuous thoracic impedance measurements, sleep apnea can be long-time monitored via an electronic device sensor. In the ACaSA trial, 233 patients implanted with a cardiac pacemaker (MicroPort CRM, Clamart, France) were prospectively observed between March 2022 and July 2024. For each night of follow-up, the burden of device-detected sleep apnea (DDSA) was measured via transthoracic impedance, defined by a respiratory disturbance index (RDI) ≥ 20 events per sleeping hour. Local meteorological data including maximum ambient diurnal temperature, humidity, precipitation and air pressure change were extracted from the national weather system and linked to the individual patient's place of residence. The association between these weather conditions and RDI in the following night was estimated using a generalised linear mixed effects model. Overall, 74,031 patient-nights of 210 individuals (median age 75.7 years [IQR 69.9-81.3], 77 [36.7%] female) with a median follow up of 593 nights (IQR 348-755) were analysed. In a multivariate regression analysis, ambient maximum diurnal temperature was independently associated with presence of DDSA. Following days with a maximum of 30°C, the odds of experiencing severe DDSA increased by 1.34 (95% CI: 1.17-1.54, p < 0.001) compared to days with only 10°C. Higher relative humidity increased the odds for suffering from severe DDSA as well (OR 1.19 [1.07-1.33] in 90% relative humidity vs. 65% humidity; p = 0.007). These associations of ambient maximum diurnal temperature and relative humidity with severe DDSA the following night need further investigations, in particular in view of upcoming global climate changes.

Indexed as

Pacemaker, ArtificialSleep Apnea SyndromesWeatherAgedAged, 80 and overFemaleFranceHumansMalePolysomnographyProspective StudiesSeverity of Illness Indexambient temperaturecontinuous monitoringenvironmental exposomehumiditytransthoracic impedance sensor

Identifiers

PMID39972563
PMCPMC12426709

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.