ArticleNature2025
Dual regulation of mitochondrial fusion by Parkin-PINK1 and OMA1.
Abstract read
In one paragraph
Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed.
- Age-dependent mitochondrial toxicity in renal stem cells: A precise 3D silk matrix model.Genes & diseases · 2026Article
- Ultrasound-Responsive Piezoelectric Fibrous Membrane Promotes Neurological Recovery After TBI by Modulating Microglial Polarization via Restoring Mitochondrial Dynamic Homeostasis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Article
- Mitophagy-mediated immune evasion: Shared strategies of pathogens.Redox biology · 2026Review
- The long-lived immune system of centenarians.Nature reviews. Immunology · 2026Review
- Article
- Mitochondrial Quality Control in Age-Related Diseases: From Molecular Architecture to Precision Therapeutics.Antioxidants (Basel, Switzerland) · 2026Review
- AMC-F1 regulates mitochondria-autophagy crosstalk independent of nutrient stress.Nature communications · 2026Article
- Stress-induced OMA1-mediated cleavage of AIFM1 suppresses cell growth by controlling mitochondrial OXPHOS activity.The EMBO journal · 2026Article
- Pathogenic variants in the autophagy-tethering factor EPG5 drive neurodegeneration through mitochondrial dysfunction and innate immune activation.Nature communications · 2026Article
- The emerging role and therapeutic targeting of autophagy-lysosome pathway in the pathogenesis of Parkinson's disease.Translational neurodegeneration · 2026Review
- ALCAT1 promotes diabetic cardiomyopathy by linking myocardial tetralinoleoyl cardiolipin deficiency to lipotoxicity.Molecular therapy : the journal of the American Society of Gene Therapy · 2026Article
- A robust workflow for 3D imaging of human mitochondria using cryo-electron tomography.bioRxiv : the preprint server for biology · 2026Article
- Mitochondrial Homeostasis in Diabetic Cardiomyopathy: From Dysfunction to Therapeutic Strategies.Antioxidants (Basel, Switzerland) · 2026Review
- From Population Averaging to Single Event Resolution: Evolution of Sensing Platforms for Membrane Fusion.Sensors (Basel, Switzerland) · 2026Review
- Stress adaptation of mitochondrial protein import by OMA1-mediated degradation of DNAJC15.Nature structural & molecular biology · 2026Article
- Dual regulation of PINK1/PARKIN-mediated mitochondrial autophagy in ovarian cancer progression and drug resistance: mechanisms and therapeutic potentials.Journal of ovarian research · 2026Review
- Mitochondrial remodeling and metabolic reprogramming drive long-term salinity adaptation inmSystems · 2026Article
- Milk fat globule-EGF factor 8/ATP-binding cassette subfamily E member 1 axis maintains mitophagy flux homeostasis to suppress ferroptosis in acute pancreatitis.Clinical and translational medicine · 2026Article
- Organelle-specific regulation of ferroptosis.Biology direct · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors.
Tatsuya Yamada *Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Arisa Ikeda *Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Daisuke MurataDepartment of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Hu WangNeuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Cissy ZhangDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Pratik KhareDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0002-1633-8765
Yoshihiro AdachiDepartment of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Fumiya ItoDepartment of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Pedro M QuirósDepartamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, Oviedo, Spain.ORCID 0000-0002-7793-6291
Seth BlackshawDepartment of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Carlos López-OtínDepartamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, Oviedo, Spain.
Thomas LangerMax Planck Institute for Biology of Ageing, Cologne, Germany.ORCID 0000-0003-1250-1462
David C ChanDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.ORCID 0000-0002-0191-2154
Anne LeDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Valina L DawsonNeuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0002-2915-3970
Ted M DawsonNeuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0002-6459-0893
Miho IijimaDepartment of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. miijima@jhmi.edu.ORCID 0000-0002-3073-9135
Hiromi SesakiDepartment of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. hsesaki@jhmi.edu.ORCID 0000-0002-6877-3929
Funding
The role of stress in the fetal origin of obesity and metabolic dysfunctionP20GM104320 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI ZEMPLENI, JANOS · 2014 to 2024
$24.9MHomeostatic Mechanisms Regulating Mitochondrial Health EQUIPMENT SUPPLEMENTR35GM127147 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI David C Chan · 2018 to 2026
$6.0MRegulation of Intracellular SignalingR35GM131768 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Miho Iijima · 2019 to 2026
$4.0MStructure, Turnover and Safeguard of MitochondriaR35GM144103 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Hiromi Sesaki · 2022 to 2026
$2.8MDevelopment and function of hypothalamic Lhx6-positive neuronsR01MH126676 · NIMH · JOHNS HOPKINS UNIVERSITY · PI BLACKSHAW, SETH · 2021 to 2025
$2.0MNIGMS NIH HHS P20 GM104320NIGMS NIH HHS R35 GM127147NIGMS NIH HHS R35 GM131768NIGMS NIH HHS R35 GM144103NIMH NIH HHS R01 MH126676
Abstract
Mitochondrial stress pathways protect mitochondrial health from cellular insults
Indexed as
MetalloendopeptidasesMitochondriaMitochondrial DynamicsMitochondrial ProteinsProtein KinasesUbiquitin-Protein LigasesAnimalsFemaleGTP PhosphohydrolasesMaleMetalloproteasesMiceMice, KnockoutMitochondrial MembranesPTEN-Induced Putative KinaseGTP PhosphohydrolasesMetalloendopeptidasesMetalloproteasesMfn1 protein, mouseMitochondrial ProteinsOMA1 protein, mouseOpa1 protein, mouseparkin proteinProtein KinasesPTEN-Induced Putative KinaseUbiquitin-Protein Ligases
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.