Evidence map›Paper›PMID 39971934›Full record

ArticleScientific data2025

Complete genome and transcriptome datasets of Streptococcus salivarius strains from healthy Korean subjects.

Eun-Young Jang, Ji-Hoi Moon, Jae-Hyung Lee

Abstract readDataset
In one paragraph

Article in Scientific data, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Eun-Young JangDepartment of Oral Microbiology, College of Dentistry, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, Republic of Korea.
Ji-Hoi MoonDepartment of Oral Microbiology, College of Dentistry, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, Republic of Korea. prudence75@khu.ac.kr.
Jae-Hyung LeeDepartment of Oral Microbiology, College of Dentistry, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, Republic of Korea. jaehlee@khu.ac.kr.ORCID http://orcid.org/0000-0002-5085-6988

Funding

National Research Foundation of Korea (NRF) NRF-2021R1A2C2008180
6 · The paper itself

Abstract

The oral microbiome plays a crucial role in maintaining health, with Streptococcus salivarius recognized for its beneficial probiotic functions, including inhibiting pathogenic bacteria and supporting immune regulation, particularly in healthy individuals. While research on S. salivarius has primarily focused on strains originating from non-Asian populations, particularly New Zealand, with some studies also reporting European strains, research on strains originating from Korea has been notably lacking. This dataset provides the complete genome sequences and transcriptomic profiles of 12 S. salivarius strains isolated from healthy Korean individuals. PacBio SMRTbell technology was employed for genome sequencing. Our dataset includes transcriptomic data that reveal functional gene expression patterns under standard growth conditions. The strains analyzed here are particularly valuable as each exhibits a unique interaction with Fusobacterium nucleatum, a pathogen associated with periodontal disease and colorectal cancer, collectively demonstrating diverse patterns of interaction. By offering comprehensive data on strain variation, this resource can serve as a valuable tool for research aimed at understanding and utilizing beneficial oral bacteria.

Indexed as

Genome, BacterialStreptococcus salivariusTranscriptomeFusobacterium nucleatumHealthy VolunteersHumansMouthRepublic of Korea

Identifiers

PMID39971934
PMCPMC11840143

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.