ReviewDigestive diseases and sciences2025
Application of the Colorectal Cancer (CRC) Screening Guiding Principles for Non-invasive Testing to Multi-target Stool DNA: A Case Study.
Review in Digestive diseases and sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- The evolving role of OMICS in gastrointestinal tumor biology and clinical practice.Molecular cancer · 2026Review
- Global burden and projection of colorectal cancer attributable to low whole-grain diets: an analysis of GBD 2021 data with Bayesian age-period-cohort modeling.Frontiers in oncology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A significant lack of participation in colorectal cancer (CRC) screening programs in the United States limits the impact of screening to reduce morbidity and mortality. Recently a group of experts in CRC screening defined the Guiding Principles for Noninvasive Testing (GPNIT). GPNIT pathway is intended to serve as a step by step guide for study design to ultimately lead to implementation and integration of a potentially clinically appropriate CRC screening test. Multi-target stool DNA (MT-sDNA) test usage for CRC screening has increased significantly recently in the United States. Here, the key studies in the development of MT-sDNA as an emerging CRC screening test are placed in context of the GPNIT pathway for CRC screening test development. This case study is meant to be instructive for future test development in CRC screening to achieve ultimately clinically relevant future tests and improve the efficacy of CRC screening.
Indexed as
Identifiers
39971827What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.