Evidence map›Paper›PMID 39971799›Full record

ArticleNeurosurgical review2025

MR‑guided laser interstitial thermal therapy followed by early application of temozolomide for recurrent IDH-wildtype glioblastomas: preliminary results from a prospective study.

Xuzhe Zhao, Chao Li, Kai Wang, Yutao Zhang, Haibin Wan, Pei Yang, Dabiao Zhou

Abstract read
PubMed Publisher
In one paragraph

Article in Neurosurgical review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xuzhe ZhaoDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No.119 South Fourth Ring West Road, Fengtai District, Beijing, 100070, China.
Chao LiDepartment of Neurosurgery, First Affiliated Hospital, Guangxi Medical University, Nanning, China.
Kai WangDepartment of Nuclear Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Yutao ZhangDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No.119 South Fourth Ring West Road, Fengtai District, Beijing, 100070, China.
Haibin WanDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No.119 South Fourth Ring West Road, Fengtai District, Beijing, 100070, China.
Pei YangDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No.119 South Fourth Ring West Road, Fengtai District, Beijing, 100070, China.
Dabiao ZhouDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, No.119 South Fourth Ring West Road, Fengtai District, Beijing, 100070, China. dabiaozhou@163.com.ORCID http://orcid.org/0000-0002-2683-2580

Funding

National Natural Science Foundation of China 82151310
6 · The paper itself

Abstract

This study aims to evaluate the safety, tolerability, and preliminary efficacy of combining laser interstitial thermal therapy (LITT) with early administration of temozolomide (TMZ) in patients with recurrent glioblastoma (rGBM). Ten patients with rGBM were enrolled. Following the LITT procedure, TMZ was administered at a dose of 75 mg/m

Indexed as

Antineoplastic Agents, AlkylatingBrain NeoplasmsGlioblastomaLaser TherapyNeoplasm Recurrence, LocalTemozolomideAdultAgedCombined Modality TherapyFemaleHumansIsocitrate DehydrogenaseMagnetic Resonance ImagingMaleMiddle AgedProspective StudiesAntineoplastic Agents, AlkylatingIsocitrate DehydrogenaseTemozolomideGlioblastomaLaser ablationLITTRecurrence

Identifiers

PMID39971799

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.