Evidence map›Paper›PMID 39971787›Full record

ArticleWorld journal of urology2025

Comparative analysis of trifecta and pentafecta outcomes in T1a and T1b renal tumors following robotic partial nephrectomy: a retrospective study.

Rakesh Sharma, S Lohith, Amaresh Mohan, Bhasker Reddy, Rohit Singh, Manoj Kharadae, Vivek Meyyappan, Srikanth Srirama

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in World journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

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2citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Rakesh SharmaBasavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, India.
S LohithBasavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, India. lohith.uro@gmail.com.
Amaresh MohanBasavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, India.
Bhasker ReddyBasavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, India.
Rohit SinghBasavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, India.
Manoj KharadaeBasavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, India.
Vivek MeyyappanBasavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, India.
Srikanth SriramaBasavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aims to conduct a comparative analysis of Trifecta and Pentafecta outcomes between T1a and T1b renal tumors in patients undergoing robotic partial nephrectomy (RAPN). We explore the influence of clinical factors, including the RENAL nephrometry score components, on these outcomes.

methodsA retrospective single centre study was conducted on 133 patients who underwent RAPN for T1a (n = 51) and T1b (n = 82) renal tumors between 2017 and 2023. We assessed Trifecta and Pentafecta outcomes, and statistical comparisons were made. Univariate and multivariate analyses were conducted to evaluate the impact of tumor size and RENAL components on these outcomes.

resultsTrifecta was achieved in 84.3% of T1a tumors and 85.36% of T1b tumors (p = 0.86). Pentafecta outcomes were achieved in 60.8% of T1a and 41.46% of T1b tumors (p = 0.34). Warm ischemia time was significantly longer in T1b tumors (p = 0.037). In the univariate analysis, warm ischemia time and tumor size were significant predictors of Trifecta and Pentafecta outcomes, respectively. Nearness to the collecting system was also a significant factor in univariate analysis (p = 0.045). Other clinical factors such as exophytic/endophytic properties and location relative to polar lines did not significantly impact outcomes.

conclusionRAPN is equally effective for T1a and T1b renal tumors, providing comparable Trifecta and Pentafecta outcomes. Warm ischemia time, tumor size, and nearness to the collecting system are important factors influencing these outcomes.

Indexed as

KidneyKidney NeoplasmsNephrectomyRobotic Surgical ProceduresAdultAgedFemaleGlomerular Filtration RateHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeWarm IschemiaCollecting system proximityPentafectaRENAL nephrometry scoreRobotic partial nephrectomyT1a renal tumorT1b renal tumorTrifectaWarm ischemia time

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.