Evidence map›Paper›PMID 39971291›Full record

ArticleInternal medicine (Tokyo, Japan)2025

Helicobacter pylori-positive Colorectal MALT Lymphoma with Repeated Metachronous Recurrence after a Complete Response to Eradication Therapy and Regression after a Watch-and-wait Strategy.

Daisuke Shimizu, Hidehiko Takigawa, Yuki Kitadai, Misa Ariyoshi, Ryo Miyamoto, Yuichi Hiyama, Yuji Urabe, Akira Ishikawa, Toshio Kuwai, Shiro Oka

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daisuke ShimizuDepartment of Gastroenterology, Hiroshima University Hospital, Japan.
Hidehiko TakigawaDepartment of Gastroenterology, Hiroshima University Hospital, Japan.
Yuki KitadaiDepartment of Gastroenterology, Hiroshima University Hospital, Japan.
Misa AriyoshiDepartment of Gastroenterology, Hiroshima University Hospital, Japan.
Ryo MiyamotoDepartment of Gastroenterology, Hiroshima University Hospital, Japan.
Yuichi HiyamaDepartment of Gastroenterology, Hiroshima University Hospital, Japan.
Yuji UrabeDepartment of Gastroenterology, Hiroshima University Hospital, Japan.
Akira IshikawaGraduate School of Biomedical and Health Sciences, Hiroshima University, Japan.
Toshio KuwaiDepartment of Gastrointestinal Endoscopy and Medicine, Hiroshima University Hospital, Japan.
Shiro OkaDepartment of Gastroenterology, Hiroshima University Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 77-year-old man underwent a colonoscopy. A submucosal cecal tumor was found, and localized colorectal MALT lymphoma (Lugano stage I) was diagnosed with a Helicobacter pylori infection. The first-line eradication therapy was successful, and the cecal lesion regressed. However, a new lesion was observed in the lower rectum. The rectal lesion regressed after the second-line eradication therapy. Two new lesions were identified in the sigmoid colon. However, no additional treatment was administered and a watch-and-wait strategy was adopted. Both of the lesions regressed. There are no established treatments for colorectal MALT lymphomas. The watch-and-wait strategy may be effective in cases of recurrence after eradication therapy.

Indexed as

Colorectal NeoplasmsHelicobacter InfectionsHelicobacter pyloriLymphoma, B-Cell, Marginal ZoneNeoplasm Recurrence, LocalAgedAnti-Bacterial AgentsHumansMaleAnti-Bacterial AgentscolonHelicobacter pyloriMALT lymphomarecurrencewatch-and-wait

Identifiers

PMID39971291
PMCPMC12425579

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.