Evidence map›Paper›PMID 39971132›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2025

Association between out-of-sequence allocation and deceased donor kidney nonuse across organ procurement organizations.

Joel T Adler, David C Cron, Arnold E Kuk, Miko Yu, Sumit Mohan, S Ali Husain, Layla Parast

Abstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Out-of-Sequence Placement of Deceased Donor Kidneys Is Exacerbating Inequities in the United States.Clinical journal of the American Society of Nephrology : CJASN · 2026
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Joel T AdlerDivision of Transplantation, Department of Surgery and Perioperative Care, Dell Medical School at the University of Texas at Austin, Austin, Texas, USA. Electronic address: joel.adler@austin.utexas.edu.
David C CronCenter for Surgery and Public Health at Brigham and Women's Hospital, Boston, Massachusetts, USA; Massachusetts General Hospital, Boston, Massachusetts, USA.
Arnold E KukDepartment of Statistics and Data Science, University of Texas at Austin, Austin, Texas, USA.
Miko YuColumbia University Renal Epidemiology (CURE) Group, Division of Nephrology, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA.
Sumit MohanColumbia University Renal Epidemiology (CURE) Group, Division of Nephrology, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA; Division of Nephrology, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA.
S Ali HusainColumbia University Renal Epidemiology (CURE) Group, Division of Nephrology, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA; Division of Nephrology, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA.
Layla ParastBiomedical Data Sciences Hub, Dell Medical School at the University of Texas at Austin, Austin, Texas, USA.

Funding

Using Decision Making Science to Optimize Deceased Donor Kidney AllocationK23DK133729 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI HUSAIN, SYED ALI · 2022 to 2025
$678k
AHRQ HHS K08 HS028476NIDDK NIH HHS K23 DK133729
6 · The paper itself

Abstract

Out-of-sequence (OOS) kidney allocation has become increasingly prevalent since 2021. We examined the relationship between organ procurement organization (OPO) OOS allocation frequency and kidney nonuse rates. Among 57 OPOs between March 2021 and December 2023, we analyzed trends in OOS utilization and its association with kidney nonuse rates. There was significant variability in OOS use across OPOs, with some allocating over 20% of kidneys out-of-sequence over the entire period. An absolute increase of 1 SD (12.8%) of OOS allocation was modestly associated with a reduction in kidney nonuse rates (incidence risk ratio = 0.98; P = .04). Donor characteristics, particularly older age, donation after circulatory death, and high kidney donor profile index, were the strongest predictors of nonuse. While OOS allocation may mitigate logistical challenges, other strategies may be more effective at reducing the nonuse rate.

Indexed as

Kidney TransplantationResource AllocationTissue and Organ ProcurementTissue DonorsAdultFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisRetrospective StudiesWaiting Listsaccess to careallocationdisparitiesout-of-sequence allocationpolicy

Identifiers

PMID39971132
PMCPMC12310372

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.