Evidence map›Paper›PMID 39970873›Full record

ArticleCell reports. Medicine2025

KRAS

Xiangyan Jiang, Tao Wang, Bin Zhao, Haonan Sun, Yuman Dong, Yong Ma, Zhigang Li, Yuxia Wu, Keshen Wang, Xiaoying Guan and 15 more

Abstract read
In one paragraph

Article in Cell reports. Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Discovery of a novel and potent KRASJournal of enzyme inhibition and medicinal chemistry · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. KRASScience advances · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Xiangyan JiangDepartment of General Surgery, Lanzhou University Second Hospital, Lanzhou 730000, China; The Second Clinical Medical School, Lanzhou University, Lanzhou 730000, China.
Tao WangDepartment of General Surgery, Lanzhou University Second Hospital, Lanzhou 730000, China; The Second Clinical Medical School, Lanzhou University, Lanzhou 730000, China.
Bin ZhaoDepartment of General Surgery, Lanzhou University Second Hospital, Lanzhou 730000, China; The Second Clinical Medical School, Lanzhou University, Lanzhou 730000, China.
Haonan SunDepartment of General Surgery, Lanzhou University Second Hospital, Lanzhou 730000, China; The Second Clinical Medical School, Lanzhou University, Lanzhou 730000, China.
Yuman DongGansu Province High-Altitude High-Incidence Cancer Biobank, Lanzhou University Second Hospital, Lanzhou 730000, China; Cuiying Biomedical Research Center, Lanzhou University Second Hospital, Lanzhou 730000, China; State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China.
Yong MaDepartment of General Surgery, Lanzhou University Second Hospital, Lanzhou 730000, China; The Second Clinical Medical School, Lanzhou University, Lanzhou 730000, China.
Zhigang LiThe Second Clinical Medical School, Lanzhou University, Lanzhou 730000, China.
Yuxia WuThe Second Clinical Medical School, Lanzhou University, Lanzhou 730000, China.
Keshen WangDepartment of General Surgery, Lanzhou University Second Hospital, Lanzhou 730000, China; The Second Clinical Medical School, Lanzhou University, Lanzhou 730000, China.
Xiaoying GuanDepartment of Pathology, Lanzhou University Second Hospital, Lanzhou 730000, China.
Bo LongDepartment of General Surgery, Lanzhou University Second Hospital, Lanzhou 730000, China.
Long QinGansu Province High-Altitude High-Incidence Cancer Biobank, Lanzhou University Second Hospital, Lanzhou 730000, China; Cuiying Biomedical Research Center, Lanzhou University Second Hospital, Lanzhou 730000, China.
Wengui ShiGansu Province High-Altitude High-Incidence Cancer Biobank, Lanzhou University Second Hospital, Lanzhou 730000, China; Cuiying Biomedical Research Center, Lanzhou University Second Hospital, Lanzhou 730000, China.
Lei ShiSchool of Public Health, Lanzhou University, Lanzhou 730000, China.
Qichen HeDepartment of General Surgery, Lanzhou University Second Hospital, Lanzhou 730000, China; The Second Clinical Medical School, Lanzhou University, Lanzhou 730000, China.
Wenbo LiuThe Second Clinical Medical School, Lanzhou University, Lanzhou 730000, China.
Mingdou LiThe Second Clinical Medical School, Lanzhou University, Lanzhou 730000, China.
Lixia XiaoDepartment of General Surgery, Lanzhou University Second Hospital, Lanzhou 730000, China; The Second Clinical Medical School, Lanzhou University, Lanzhou 730000, China.
Chengliang ZhouRadboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6500 HB Nijmegen, the Netherlands.
Hui SunCuiying Biomedical Research Center, Lanzhou University Second Hospital, Lanzhou 730000, China.
Jing YangCuiying Biomedical Research Center, Lanzhou University Second Hospital, Lanzhou 730000, China.
Junhong GuanCuiying Biomedical Research Center, Lanzhou University Second Hospital, Lanzhou 730000, China.
Huinian ZhouDepartment of General Surgery, Lanzhou University Second Hospital, Lanzhou 730000, China.
Zeyuan YuDepartment of General Surgery, Lanzhou University Second Hospital, Lanzhou 730000, China; Gansu Province High-Altitude High-Incidence Cancer Biobank, Lanzhou University Second Hospital, Lanzhou 730000, China.
Zuoyi JiaoDepartment of General Surgery, Lanzhou University Second Hospital, Lanzhou 730000, China; Gansu Province High-Altitude High-Incidence Cancer Biobank, Lanzhou University Second Hospital, Lanzhou 730000, China. Electronic address: jiaozy@lzu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The KRAS

Indexed as

Carcinoma, Pancreatic DuctalPancreatic NeoplasmsPentose Phosphate PathwayProto-Oncogene Proteins p21(ras)AnimalsCell Line, TumorFemaleGlucosephosphate DehydrogenaseHeterocyclic Compounds, 2-RingHumansMiceNaphthalenesTumor Suppressor Protein p53Ubiquitin-Conjugating EnzymesXenograft Model Antitumor AssaysGlucosephosphate DehydrogenaseHeterocyclic Compounds, 2-RingKRASG12D inhibitor MRTX1133KRAS protein, humanNaphthalenesProto-Oncogene Proteins p21(ras)Tumor Suppressor Protein p53Ubiquitin-Conjugating EnzymesKRAS(G12D)metabolic reprogrammingMRTX1133pancreatic ductal adenocarcinomapentose phosphate pathway

Identifiers

PMID39970873
PMCPMC11866490

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.