Evidence map›Paper›PMID 39970576›Full record

ArticleDrug and alcohol dependence2025

"Ice" flavor elements in E-cigarette images: Influence on liking and intention to use among youth who are at risk of E-cigarette use.

Wei Li, Danielle R Davis, Eugenia Buta, Ralitza Gueorguieva, Nashmia Khan, Barry G Green, Kathleen A Garrison, Suchitra Krishnan-Sarin

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wei LiDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA. Electronic address: wei.vanness.li@yale.edu.
Danielle R DavisDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Eugenia ButaDepartment of Biostatistics, Yale School of Public Health, New Haven, CT, USA.
Ralitza GueorguievaDepartment of Biostatistics, Yale School of Public Health, New Haven, CT, USA.
Nashmia KhanDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Barry G GreenThe John B. Pierce Laboratory, Yale School of Medicine, New Haven, CT, USA; Department of Surgery (Otolaryngology), Yale School of Medicine, New Haven, CT, USA.
Kathleen A GarrisonDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Suchitra Krishnan-SarinDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA.

Funding

Yale Center for the Study of Tobacco Product Use and Addiction (YCSTP) Project 2: Addictive Threshold of Nicotine and the Impact of SweetenersU54DA036151 · NIDA · YALE UNIVERSITY · PI LISA M FUCITO · 2018 to 2026
$41.6M
NIDA NIH HHS U54 DA036151
6 · The paper itself

Abstract

introduction"Ice"-flavored e-liquids and e-cigarettes, marketed as both sweet and cooling recently entered the US marketplace and are popular among youth. Advertisements featuring attractive product images and descriptions are one of the first exposures to these products for youth. This study examines the appeal of e-cigarette images, with and without a cooling "ice" imagery, among youth who have limited e-cigarette use or who are at risk of future use.

methodsWe conducted two online, within-subject experimental studies with 71 Connecticut youth at risk of e-cigarette use, using a Qualtrics survey. Participants viewed 34 images of sweet-flavored e-liquids with and without cooling imagery (e.g., mango vs. mango-ice) and 28 sweet-flavored disposables devices with (e.g., watermelon-ice) and without names indicating cooling (e.g., strawberry). Images were presented in randomized order and participants rated overall liking and intention to use on four-point scales. Linear mixed-effects models were used to analyze outcomes, reporting least-squares means (M) and standard errors (SE).

resultsThe sample was 59.2 % female with an average age of 16.5 years. No significant differences were observed for liking and intention to use between sweet-flavored e-liquids with and without cooling imagery (ps > 0.05). For disposable e-cigarette images, participants reported significantly higher overall liking (M = 1.72, [SE = 0.07] vs. 1.62 [0.07], p = 0.002) and intention to use (1.52 [0.06] vs. 1.46 [0.06]; p = 0.037) in response to images without descriptions of "ice" compared to those with "ice".

conclusionsAdding cooling images or descriptors did not increase appeal or use intentions of sweet-flavored e-liquids or disposable e-cigarettes among youth with limited e-cigarette experience.

Indexed as

AdvertisingElectronic Nicotine Delivery SystemsFlavoring AgentsIntentionVapingAdolescentFemaleHumansMaleFlavoring AgentsCooling flavorsE-cigarettes“ice” flavorsYouth

Identifiers

PMID39970576
PMCPMC12919728

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.