Evidence map›Paper›PMID 39970217›Full record

ArticleScience advances2025

Large closed-basin lakes sustainably supplied phosphate during the origins of life.

Craig R Walton, Jihua Hao, Maria Schönbächler, Oliver Shorttle

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Craig R WaltonInstitute of Astronomy, University of Cambridge, Madingley Road, Cambridge CB3OHA, UK.ORCID 0000-0003-2659-644X
Jihua HaoDeep Space Exploration Lab/CAS Key Laboratory of CrustMantle Materials and Environments, University of Science and Technology of China, 96 Jinzhai Rd., Hefei 230026, China.ORCID 0000-0003-3657-050X
Maria SchönbächlerDepartment of Earth Sciences, Institute für Geochemie und Petrologie, ETH Zurich, NW D 81.2, Clausiusstrasse 25, Zurich 8092, Switzerland.ORCID 0000-0003-4304-214X
Oliver ShorttleInstitute of Astronomy, University of Cambridge, Madingley Road, Cambridge CB3OHA, UK.ORCID 0000-0002-8713-1446

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The origin of life on Earth required a supply of phosphorus (P) for the synthesis of universal biomolecules. Closed lakes may have accumulated high P concentrations on early Earth. However, it is not clear whether prebiotic P uptake in such settings would then have been sustainable. We show that large closed-basin lakes can combine high P concentrations at steady state with extremely high rates of biological productivity. Our case study is Mono Lake in California, which has close to 1 millimolar dissolved P at steady state despite extremely high rates of biological productivity, in contrast to smaller closed basins where life is scarce. Hence, large closed-basin lakes offer an environment where high rates of prebiotic P productivity can plausibly coexist with high steady-state P concentrations. Such lakes should have readily formed on the heavily cratered and volcanically active surface of early Earth.

Identifiers

PMID39970217
PMCPMC11837993

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.